Alpha-溴苯乙酸乙酯合成路线 （共 19 条）
反应条件
thionyl chloride T=0 - 50°C;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2009/121919 A1, 2009 ;
Location in patent: Page/Page column 163 ;
WO 2009/121919 A1
反应条件
9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran T=65°C; Reformatsky Reaction; 5 h; Inert atmosphereSealed tube; chemoselective reaction;
参考文献
Wong, Brian; Linghu, Xin; Crawford, James J.; Drobnick, Joy; Lee, Wendy; Zhang, Haiming
Tetrahedron, 2014 , vol. 70, # 7 p. 1508 - 1515
反应条件
potassium carbonate in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
US2011/224304 A1, ;
Page/Page column 12 ;
参考文献
Journal of the Chemical Society, , p. 71
Journal of the Chemical Society, , p. 1251,1254
反应条件
1,5-hexadienerhodium(I) chloride dimer T=75°C; P=760 Torr; Heatingovernight; other solvent;
参考文献
Woell, James B.; Alper, Howard
Tetrahedron Letters, 1984 , vol. 25, # 35 p. 3791 - 3794
反应条件
sodium peroxodisulphate; N-bromosuccinmide; trifluorormethanesulfonic acid; palladium diacetate in 1,2-dichloro-ethane T=60°C; 2 h; Sealed tube; regioselective reaction;
参考文献
Sun, Xiuyun; Shan, Gang; Sun, Yonghui; Rao, Yu
Angewandte Chemie - International Edition, 2013 , vol. 52, # 16 p. 4440 - 4444
Angew. Chem., 2013 , vol. 125, # 16 p. 4536 - 4540,5
反应条件
1: <PhCH2NMe3>OH / methanol; tetrahydrofuran / 46 h / Heating 2: HCl / 3 h / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 52, p. 2013 - 2022
反应条件
ethanol; silver(l) oxide
参考文献
Helvetica Chimica Acta, , vol. 34, p. 1050,1059
反应条件
hydrogenchloride 3 h; Heating;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 52, p. 2013 - 2022
