2,2,5,5-四甲基-3-吡啉-1-氧基-3-羧酸合成路线 (共 10 条)
反应条件
3,3-dimethyldioxirane in acetone T=0°C;
参考文献
Murray, Robert W.; Singh, Megh
Tetrahedron Letters, 1988 , vol. 29, # 37 p. 4677 - 4680
反应条件
sodium hydroxide Heating;
参考文献
Groesbeek, M.; Lugtenburg, J.
Recueil des Travaux Chimiques des Pays-Bas, 1995 , vol. 114, # 9/10 p. 403 - 409
反应条件
sodium hydroxide; dihydrogen peroxide in methanol T=20°C; 24 h;
参考文献
Tetrahedron Letters, , vol. 43, # 45 p. 8125 - 8127
反应条件
hydroxylamine in ethanol; benzene 0.25 h;
参考文献
Russian Journal of Organic Chemistry, , vol. 45, # 8 p. 1189 - 1199
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 12 h;
参考文献
Molecules, , vol. 5, # 12 p. 1244 - 1250
反应条件
1: 50 percent / Dicyclohexylcarbodiimide / ethyl acetate / 3 h / Ambient temperature 2: 47 percent / NaBH4 / ethanol / 6 h / Ambient temperature View Scheme
参考文献
Hideg, K.; Hankovszky, H. O.; Lex, L.; Kulcsar, Gy.
Synthesis, 1980 , # 11 p. 911 - 914
反应条件
1: SOCl2, pyridine / benzene / 6 - 8 °C 2: LiAlH(O-tBu)3 / tetrahydrofuran / 1 h / -70 °C 3: 83 percent / C2H5ONa / 2 h / 0 °C View Scheme
参考文献
Mustafi, Devkumar; Boisvert, William E.; Makinen, Marvin W.
Journal of the American Chemical Society, 1993 , vol. 115, # 9 p. 3674 - 3682
参考文献
Crouch, Rosalie K.; Ebrey, Thomas G.; Govindjee, Rajni
Journal of the American Chemical Society, 1981 , vol. 103, # 24 p. 7364 - 7366
参考文献
Liu, Ying-Qian; Dai, Wei; Tian, Jing; Yang, Liu; Feng, Gang; Zhou, Xing-Wen; Kou, Liang; Zhao, Yong-Long; Li, Wen-Qun; Li, Lin-Hai; Li, Hong-Yu
Heteroatom Chemistry, 2011 , vol. 22, # 6 p. 687 - 691
反应条件
1: SOCl2; pyridine / benzene
2: LiAlH(O-t-Bu)3 / tetrahydrofuran / -78 - 20 °C
View Scheme
参考文献
Groesbeek, M.; Lugtenburg, J.
Recueil des Travaux Chimiques des Pays-Bas, 1995 , vol. 114, # 9/10 p. 403 - 409