(S)-(+)-5-氧代-2-四氢呋喃羧酸合成路线 （共 30 条）
反应条件
hydrogenchloride; sodium nitrite in water T=15°C; optical yield given as percent ee;
参考文献
Montagnat, Oliver D.; Lessene, Guillaume; Hughes, Andrew B.
Journal of Organic Chemistry, 2010 , vol. 75, # 2 p. 390 - 398
反应条件
bis(tri-n-butyltin)oxide in acetonitrile T=60°C; 24 h;
参考文献
Salomon, Claudio J.; Mata, Ernesto G.; Mascaretti, Oreste A.
Journal of Organic Chemistry, 1994 , vol. 59, # 24 p. 7259 - 7266
参考文献
Stone,K.J.; Little,R.D.
Journal of the American Chemical Society, 1985 , vol. 107, p. 2495
反应条件
T=140 - 150°C; P=0.01 Torr; Yield given;
参考文献
Farmaco, Edizione Scientifica, , vol. 39, # 5 p. 473 - 476
反应条件
formic acid; methanesulfonic acid 6 h; Heating;
参考文献
Farmaco, Edizione Scientifica, , vol. 39, # 11 p. 963 - 967
反应条件
toluene-4-sulfonic acid in benzene
参考文献
Pirillo; Leggeri; Traverso
Farmaco, Edizione Scientifica, 1984 , vol. 39, # 5 p. 473 - 476
反应条件
1: diethyl ether 2: conc. HCl / 48 h / Ambient temperature View Scheme
参考文献
Berti, Giancarlo; Caroti, Paola; Catelani, Giorgio; Monti, Luigi
Carbohydrate Research, 1983 , vol. 124, p. 35 - 42
反应条件
dimethylsulfide borane complex
参考文献
Harmange, Jean-Christophe; Figadere, Bruno; Hocquemiller, Reynald
Tetrahedron: Asymmetry, 1991 , vol. 2, # 5 p. 347 - 350
反应条件
1: (S)-(+)-5-oxo-tetrahydrofuran-2-carboxylic acid With dimethylsulfide borane complex in chloroform T=61°C; 2: acetone With toluene-4-sulfonic acid
参考文献
Ikeda, Shuhei; Shibuya, Masatoshi; Iwabuchi, Yoshiharu
Chemical Communications, 2007 , # 5 p. 504 - 506
反应条件
1: (S)-(+)-5-oxo-tetrahydrofuran-2-carboxylic acid With thionyl chloride 4 h; Heating; 2: methanol With triethylamine in dichloromethane T=20°C; 12 h; Further stages.;
参考文献
Huang, Pei-Qiang; Chen, Guo; Zheng, Xiao
Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 2 p. 499 - 501
