3-(羟基甲基)-1-哌啶羧酸乙酯合成路线 (共 3 条)
反应条件
1: in tetrahydrofuran T=20°C; 0.166667 h; 2: With sodium tris(acetoxy)borohydride; acetic acid in tetrahydrofuran T=20°C;
参考文献
Ye, Xiaocong Michael; Garofalo, Albert W.; Lawler, Rose D.; Fukuda, Juri Y.; Konradi, Andrei W.; Holcomb, Ryan; Rossiter, Kassandra I.; Wone, David W.G.; Wu, Jing
Patent: US2007/32475 A1, 2007 ;
Location in patent: Page/Page column 42 ;
US 20070032475 A1
反应条件
in chloroform; water
参考文献
Janssen Pharmaceutica N.V.
Patent: US6156757 A1, 2000 ;
US 6156757 A
反应条件
triethylamine in water; acetone
参考文献
Deyine, Abdallah; Poirier, Jean-Marie; Duhamel, Lucette; Duhamel, Pierre
Tetrahedron Letters, 2005 , vol. 46, # 14 p. 2491 - 2493