2,4-二氯-1-苯乙烯合成路线 （共 10 条）
反应条件
Methyltriphenylphosphonium bromide; potassium carbonate in 1,4-dioxane T=125°C; 18 h;
参考文献
Guelak, Samet; Jacobivonwangelin, Axel
Angewandte Chemie - International Edition, 2012 , vol. 51, # 6 p. 1357 - 1361
反应条件
1: triphenyl-methyl-phosphonium iodide With potassium tert-butylate in tetrahydrofuran T=0°C; 1 h; Inert atmosphere; 2: 2,4-di-(chloro)-benzaldehyde in tetrahydrofuran T=20°C; Inert atmosphere;
参考文献
Zhang, Guofu; Xie, Xiaoqiang; Wang, Yong; Wen, Xin; Zhao, Yun; Ding, Chengrong
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 18 p. 2947 - 2950
反应条件
potassium carbonate in 1,4-dioxane Wittig Olefination; 18 h;
参考文献
Guelak, Samet; Gieshoff, Tim N.; Von Wangelin, Axel Jacobi
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 11-12 p. 2197 - 2202
反应条件
1: With sodium hydride in pyridine T=40°C; Metallation; 0.25 h; 2: With copper(l) chloride in pyridine Cyclization; Ullman reaction; 4 h; Heating;
参考文献
Zhu, Jingyang; Price, Benjamin A.; Zhao, Shannon X.; Skonezny, Paul M.
Tetrahedron Letters, 2000 , vol. 41, # 21 p. 4011 - 4014
参考文献
Walling; Wolfstirn
Journal of the American Chemical Society, 1947 , vol. 69, p. 852
反应条件
1: pinacolboratamethylenetriphenylphosphonium iodide With lithium hexamethyldisilazane in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=0°C; 2 h; 2: 2,4-di-(chloro)-benzaldehyde in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=-78 - 20°C;
参考文献
Al-Aziz Quntar, Abed; Srebnik, Morris
Synthetic Communications, 2002 , vol. 32, # 16 p. 2575 - 2579
反应条件
aluminum oxide T=350 - 400°C;
参考文献
Koton et al.
Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 489; engl. Ausg. S. 551
反应条件
1: aluminium isopropylate; isopropyl alcohol 2: Al2O3 / 350 - 400 °C / <760 View Scheme
参考文献
Koton et al.
Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 489; engl. Ausg. S. 551
反应条件
Multistep reaction.;
参考文献
Hansen, Anne-Lene L.; Murray, Anthony; Tanner, David
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 24 p. 4497 - 4505
反应条件
perchloric acid; oxygen; palladium diacetate; p-benozquinone; sodium nitrite in methanol; water T=20°C; Wacker Oxidation; 24 h; Schlenk techniqueSealed tubeGreen chemistry;
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 18 p. 2947 - 2950
