4-氨基-1H-咪唑-5-羧酸乙酯合成路线 （共 16 条）
反应条件
1: With methanesulfonic acid in ethanol 288 h; Heating / reflux; 2: With sodium hydroxide; water in water T=0°C; pH=6;
参考文献
McArthur, Silvia Gatti; Goetschi, Erwin; Wichmann, Juergen; Woltering, Thomas Johannes
Patent: US2007/72879 A1, 2007 ;
Location in patent: Page/Page column 18 ;
US 20070072879 A1
反应条件
sulfuric acid T=120°C; 24 h; Sealed tube;
参考文献
SIRTRIS PHARMACEUTICALS, INC.; CASAUBON, Rebecca, L.; NARAYAN, Radha; OALMANN, Christopher; VU, Chi, B.
Patent: WO2013/59587 A1, 2013 ;
Location in patent: Page/Page column 152 ;
反应条件
methanesulfonic acid in ethanol T=155 - 165°C; P=15751.6 Torr; Microwave irradiation;
参考文献
Hajduch, Jan; Cramer, John C.; Kirk, Kenneth L.
Journal of Fluorine Chemistry, 2008 , vol. 129, # 9 p. 807 - 810
反应条件
3-hydrazono-5α-androstan-17β-ol in ethanol; chloroform T=20°C;
参考文献
Chemistry of Heterocyclic Compounds, , vol. 40, # 11 p. 1470 - 1476
反应条件
ammonium hydroxide in ethanol 168 h; Ambient temperature;
参考文献
Liebigs Annalen der Chemie, , # 6 p. 1012 - 1020
反应条件
1: 1.) aluminium amalgam / 1.) ether, water, 0.5 h, 2.) ethanol, 4 deg C, 1 h 2: 2.6 g / CHCl3; ethanol / 2.5 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2310 - 2315
反应条件
in ethanol; chloroform 2.5 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2310 - 2315
参考文献
Zhurnal Obshchei Khimii, , vol. 29, p. 2401;engl.Ausg.S.2366
参考文献
Journal of the Chemical Society, , p. 1074,1076
反应条件
NOBF4; 1-n-butyl-3-methylimidazolium tetrafluoroborate T=0°C; Schiemann reaction; 168 h; UV-irradiation;
参考文献
Heredia-Moya, Jorge; Kirk, Kenneth L.
Journal of Fluorine Chemistry, 2007 , vol. 128, # 6 p. 674 - 678
