2-氨基-4-(对硝基苯)噻唑合成路线 （共 12 条）
反应条件
sodium hydrogen sulphate in water T=20°C; Hantzsch reaction; 0.166667 h; regioselective reaction;
参考文献
Rostamizadeh, Shahnaz; Aryan, Reza; Ghaieni, Hamid R.; Amani, Ali M.
Monatshefte fur Chemie, 2008 , vol. 139, # 10 p. 1241 - 1245
反应条件
iodine T=130 - 150°C; 0.166667 h; Neat (no solvent)Microwave irradiation;
参考文献
Caceres-Castillo, David; Carballo, Ruben M.; Tzec-Interian, Jorge A.; Mena-Rejon, Gonzalo J.
Tetrahedron Letters, 2012 , vol. 53, # 30 p. 3934 - 3936
反应条件
copper(II) bis(trifluoromethanesulfonate) in 1,2-dichloro-ethane T=80°C; 3 h;
参考文献
Yadav; Reddy, B.V. Subba; Rao, Y. Gopala; Narsaiah
Tetrahedron Letters, 2008 , vol. 49, # 15 p. 2381 - 2383
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 1 h;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5265 - 5269
反应条件
1: pyridinium bromide perbromide, HBr / acetic acid / 0.5 h / Ambient temperature 2: ethanol / 0.5 h / Heating View Scheme
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 43, # 9 p. 1497 - 1504
反应条件
pyridine in propan-1-ol Heating;
参考文献
Molecules, , vol. 5, # 9 p. 1055 - 1061
参考文献
Journal of Organic Chemistry, , vol. 24, p. 187,188, 194
反应条件
thiourea in DMF on palladium; carbon
参考文献
Boehringer Ingelheim Pharma KG
Patent: US6043254 A1, 2000 ;
US 6043254 A
反应条件
iron; ammonium chloride in water; isopropyl alcohol 1 h; Reflux;
参考文献
FUJIFILM Corporation; TATEISHI, Keiichi; FUJIE, Yoshihiko; TANAKA, Shigeaki
Patent: EP2604656 A1, 2013 ;
Location in patent: Paragraph 0298; 0300 ;
反应条件
1: iron; ammonium chloride / water; isopropyl alcohol / 1 h / |Reflux 2: iron; ammonium chloride / acetone / 0.25 h / 4 °C View Scheme
参考文献
FUJIFILM Corporation; TATEISHI, Keiichi; FUJIE, Yoshihiko; TANAKA, Shigeaki
Patent: EP2604656 A1, 2013 ;
