吡啶并[2,3-D]嘧啶-2,4(1H,3H)-二酮合成路线 （共 20 条）
反应条件
in water 0.075 h; microwave irradiation;
参考文献
Nikpour, Farzad; Paibast, Touraj
Chemistry Letters, 2005 , vol. 34, # 10 p. 1438 - 1439
反应条件
water; ammonium chloride T=80 - 200°C; 2.5 h;
参考文献
Kudos Pharmaceuticals Ltd
Patent: US2006/199804 A1, 2006 ;
Location in patent: Page/Page column 40 ;
US 20060199804 A1
反应条件
potassium hydroxide; bromine
参考文献
Journal of the Chemical Society, , p. 2582,2584
反应条件
sulfuric acid T=160°C; 2 h;
参考文献
Pfleiderer, Mathias; Pfleiderer, Wolfgang
Heterocycles, 1992 , vol. 33, # 2 p. 905 - 929
反应条件
hydrogenchloride 1 h; Heating;
参考文献
Monge, Antonio; Martinez-Merino, Victor; Sanmartin, Carmen; Fernandez, Francisco J.; Ochoa, Maria C.
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 209 - 216
反应条件
1: aqueous KMnO4 / Erwaermen des Reaktionsprodukts mit wss. HCl 2: 190 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 77, p. 2256,2259
反应条件
PPA; phosphoric acid
参考文献
Journal of the American Chemical Society, , vol. 80, p. 3449,3454
反应条件
1: 70 percent / triethylamine / CHCl3; pyridine / 15 h / Ambient temperature 2: 87 percent / N,N-dimethylformamide / ethanol / 0.25 h / Heating 3: 64 percent / 2 N hydrochloric acid / 1 h / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, p. 209 - 216
反应条件
1: 87 percent / N,N-dimethylformamide / ethanol / 0.25 h / Heating 2: 64 percent / 2 N hydrochloric acid / 1 h / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, p. 209 - 216
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 290, p. 61,65
