(2-氰基苯基)乙酸甲酯合成路线 (共 15 条)
反应条件
1: in water; N,N-dimethyl-formamide T=20°C; Heating / reflux; 2: With anhydrous iron chloride
参考文献
Le Bourdonnec, Bertrand; Ajello, Christopher William; Dolle, Roland E.
Patent: US2004/254156 A1, 2004 ;
Location in patent: Page 16 ;
反应条件
L-proline in N,N-dimethyl-formamide T=20 - 120°C; Inert atmosphere;
参考文献
Mei, Tian-Sheng; Wang, Dong-Hui; Yu, Jin-Quan
Organic Letters, 2010 , vol. 12, # 14 p. 3140 - 3143
反应条件
1: 2-methylbenzonitrile With N,N'-dimethyl-N,N'-propyleneurea; lithium diisopropyl amide in tetrahydrofuran; hexane T=-78°C; Metallation; 0.25 h; 2: methyl chloroformate in tetrahydrofuran; hexane T=-78°C; Acylation; 0.25 h;
参考文献
Bunce, Richard A.; Johnson, Lara B.
Organic Preparations and Procedures International, 1999 , vol. 31, # 4 p. 407 - 412
参考文献
Qiao; Meutermans; Wong; Traubel; Wentrup
Journal of the American Chemical Society, 1996 , vol. 118, # 16 p. 3852 - 3861
参考文献
Journal of the American Chemical Society, , vol. 118, # 16 p. 3852 - 3861
反应条件
T=700°C; Yield given. Title compound not separated from byproducts;
参考文献
Qiao; Meutermans; Wong; Traubel; Wentrup
Journal of the American Chemical Society, 1996 , vol. 118, # 16 p. 3852 - 3861
反应条件
T=850°C; Yield given;
参考文献
Journal of the American Chemical Society, , vol. 118, # 16 p. 3852 - 3861
反应条件
1: H2SO4 / Heating 2: dimethylformamide / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 10 p. 2647 - 2652
反应条件
in N,N-dimethyl-formamide Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 10 p. 2647 - 2652
反应条件
1: Diazotierung und Umsetzung mit K3<Cu(CN)4> View Scheme
参考文献
Journal of Organic Chemistry, , vol. 18, p. 30,33