2,3-二氢苯并[b][1,4]二恶英-6-羧酸乙酯合成路线 (共 4 条)
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20 - 80°C;
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
反应条件
sulfuric acid Reflux;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 4 p. 1373 - 1379
反应条件
potassium borohydride; lithium chloride 0.1 h; microwave irradiation;
参考文献
Feng; Liu; Dai; Yang; Tu
Synthetic Communications, 2001 , vol. 31, # 12 p. 1875 - 1877
反应条件
hydrazine hydrate in ethanol
24 h; Reflux;
参考文献
Du, Qian-Ru; Li, Dong-Dong; Pi, Ya-Zhou; Li, Jing-Ran; Sun, Jian; Fang, Fei; Zhong, Wei-Qing; Gong, Hai-Bin; Zhu, Hai-Liang
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 8 p. 2286 - 2297