2-甲基-4-苯基-5-甲基噁唑合成路线 （共 24 条）
参考文献
King; McMillan
Journal of the American Chemical Society, 1955 , vol. 77, p. 2814
反应条件
(n-Pr)2NLi in tetrahydrofuran
T=-78°C; 3.5 h;
参考文献
Smith, Thomas E.; Mourad, Michelle S.; Velander, Alan J.
Heterocycles, 2002 , vol. 57, # 7 p. 1211 - 1217
反应条件
1: triethylamine / diethyl ether / -78 °C
2: sodium amide / diethyl ether; liquid ammonia / 5 h / -40 °C
3: pyridine / diethyl ether / 3 h
4: 93 percent / sodium hydride / tetrahydrofuran / 0.2 h / 20 °C / other temperature, time, base
View Scheme
参考文献
Nilsson, Bjoern M.; Hacksell, Uli
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 269 - 275
反应条件
1: sodium amide / diethyl ether; liquid ammonia / 5 h / -40 °C
2: pyridine / diethyl ether / 3 h
3: 93 percent / sodium hydride / tetrahydrofuran / 0.2 h / 20 °C / other temperature, time, base
View Scheme
参考文献
Nilsson, Bjoern M.; Hacksell, Uli
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 269 - 275
反应条件
1: potassium iodide; copper(l) iodide / ethylenediamine / 120 °C / |Inert atmosphere
2: copper(l) iodide; potassium carbonate / N,N-dimethyl-formamide / 120 °C / |Inert atmosphere
View Scheme
参考文献
Liang, Hao; Ren, Zhi-Hui; Wang, Yao-Yu; Guan, Zheng-Hui
Chemistry - A European Journal, 2013 , vol. 19, # 30 p. 9789 - 9794
参考文献
Wiley
Journal of Organic Chemistry, 1947 , vol. 12, p. 43,45
反应条件
hydrogenchloride; acetyl chloride
1.) pyridine, 9h, water bath; 2.) 3h, 100 degC; Yield given. Multistep reaction;
参考文献
Bhatt, M. Vivekananda; Reddy, Gaddam Subba
Tetrahedron Letters, 1980 , vol. 21, p. 2359 - 2360
反应条件
sodium acetate; acetic acid
anschliessend Erhitzen mit Ammoniumacetat;
参考文献
Theilig
Chemische Berichte, 1953 , vol. 86, p. 96,107
反应条件
1: 1) ether, 25 deg C, overnight, 2) 0 to 25 deg C, 2-3 h
2: 95 percent / 625 °C / 1 Torr
View Scheme
参考文献
Cunico; Kuan
Journal of Organic Chemistry, 1992 , vol. 57, # 12 p. 3331 - 3336
反应条件
trifluorormethanesulfonic acid; hydrazine
1.) reflux, 2 h, 2.) CH3OH; Yield given. Multistep reaction;
参考文献
Ogura, Fumio; Otsubo, Tetsuo; Aso, Yoshio
Phosphorus, Sulfur and Silicon and the Related Elements, 1992 , vol. 67, # 1-4 p. 223 - 238
