2-氯-1-(3,4-二甲氧基苯基)乙酮合成路线 （共 9 条）
反应条件
[2,2']bipyridinyl; copper(l) chloride in 1,2-dichloro-ethane 3 h; Heating;
参考文献
Ram, Ram N.; Manoj
Journal of Organic Chemistry, 2008 , vol. 73, # 14 p. 5633 - 5635
反应条件
potassium carbonate in acetone 7 h; Heating;
参考文献
Hiratake, Jun; Inagaki, Minoru; Nishioka, Takaaki; Oda, Jun'ichi
Journal of Organic Chemistry, 1988 , vol. 53, # 26 p. 6130 - 6133
反应条件
hydrogenchloride in diethyl ether T=-20°C; 3 h;
参考文献
Hagishita, Sanji; Seno, Kaoru; Kamata, Susumu; Haga, Nobuhiro; Ishihara, Yasunobu; Ishikawa, Michio; Shimamura, Mayumi
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 7 p. 1433 - 1446
反应条件
carbon disulfide; aluminium trichloride
参考文献
Sawada,S. et al.
Chemical and Pharmaceutical Bulletin, 1977 , vol. 25, p. 3370 - 3375
反应条件
1: SOCl2 / 2 h / Ambient temperature 2: diethyl ether / 0.5 h / 0 °C 3: concd aq. HCl / diethyl ether / 3 h / -20 °C View Scheme
参考文献
Hagishita, Sanji; Seno, Kaoru; Kamata, Susumu; Haga, Nobuhiro; Ishihara, Yasunobu; Ishikawa, Michio; Shimamura, Mayumi
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 7 p. 1433 - 1446
反应条件
1: diethyl ether / 0.5 h / 0 °C 2: concd aq. HCl / diethyl ether / 3 h / -20 °C View Scheme
参考文献
Hagishita, Sanji; Seno, Kaoru; Kamata, Susumu; Haga, Nobuhiro; Ishihara, Yasunobu; Ishikawa, Michio; Shimamura, Mayumi
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 7 p. 1433 - 1446
反应条件
1: AlCl3; nitrobenzene / 40 °C 2: potassium carbonate; xylene / 130 °C View Scheme
参考文献
Stephen; Weizmann
Journal of the Chemical Society, 1914 , vol. 105, p. 1051
反应条件
2: potassium carbonate; xylene / 130 °C View Scheme
参考文献
Bargellini; Forli-Forti
Gazzetta Chimica Italiana, 1911 , vol. 41 I, p. 750
参考文献
Stephen; Weizmann
Journal of the Chemical Society, 1914 , vol. 105, p. 1051
