L-(-)-3-苯基乳酸合成路线 (共 71 条)
反应条件
sulfuric acid; water; sodium nitrite T=60°C; Flow reactor;
参考文献
Hu, Dennis X.; O'Brien, Matthew; Ley, Steven V.
Organic Letters, 2012 , vol. 14, # 16 p. 4246 - 4249
反应条件
palladium 10 on activated carbon; hydrogen in ethanol T=20°C; P=760.051 Torr; Inert atmosphere;
参考文献
Li, Shen; Zhu, Shou-Fei; Xie, Jian-Hua; Song, Song; Zhang, Can-Ming; Zhou, Qi-Lin
Journal of the American Chemical Society, 2010 , vol. 132, # 3 p. 1172 - 1179
反应条件
potassium hydroxide; beta-hydroxyethylmercaptan; sodium formate; tri-(hydroxymethyl)-methylamine; nicotinamide adenine dinucleotide in water 192 h;
参考文献
Kim,M.J.; Whitesides,G.M.
Journal of the American Chemical Society, 1988 , vol. 110, p. 2959
反应条件
phosphate buffer; nitrilase II in methanol T=37°C; pH=8; 6 h;
参考文献
DeSantis, Grace; Zhu, Zuolin; Greenberg, William A.; Wong, Kelvin; Chaplin, Jenny; Hanson, Sarah R.; Farwell, Bob; Nicholson, Lawrence W.; Rand, Cynthia L.; Weiner, David P.; Robertson, Dan E.; Burk, Mark J.
Journal of the American Chemical Society, 2002 , vol. 124, # 31 p. 9024 - 9025
反应条件
1: With (DHQD)2AQN in diethyl ether T=-78°C; 12 h; 2: With water
参考文献
Tang, Liang; Deng, Li
Journal of the American Chemical Society, 2002 , vol. 124, # 12 p. 2870 - 2871
反应条件
1: With sodium carbonate in aq. phosphate buffer T=30°C; pH=6.5; 15 h; Enzymatic reaction; 2: With sulfuric acid enantioselective reaction;
参考文献
ACS Catalysis, , vol. 4, # 3 p. 1026 - 1031
反应条件
potassium hydroxide in methanol T=20°C; 3 h;
参考文献
Burkard, Ulrike; Effenberger, Franz
Chemische Berichte, 1986 , vol. 119, # 5 p. 1594 - 1612
反应条件
potassium carbonate in methanol T=0°C; 5 h;
参考文献
Larissegger-Schnell, Barbara; Glueck, Silvia M.; Kroutil, Wolfgang; Faber, Kurt
Tetrahedron, 2006 , vol. 62, # 12 p. 2912 - 2916
反应条件
fructose 1,6-diphosphate (FDP) trisodium salt; nicotinamide adenine dinucleotide red. form; piperazine*HCl buffer; sodium formate; DL-threo-1,4-dimercapto-2,3-butanediol in water lyophilized formate dehydrogenase, mutant lactate dehydrogenase from Bacillus stearothermophilus (BSLDH), pH=6.0;
参考文献
Kallwass, Helmut K.W.; Hogan, James K.; Macfarlane, Emma L.A.; Martichonok, Valeri; Partis, Wendy; Kay, Cyril M.; Gold, Marvin; Bryan Jones
Journal of the American Chemical Society, 1992 , vol. 114, # 27 p. 10704 - 10710
反应条件
hydrogenchloride T=110 - 120°C;
参考文献
Ojima, Iwao; Zhao, Mangzhu; Yamato, Takehiko; Nakahashi, Kazuaki; Yamashita, Mitsuo; Abe, Rumiko
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5263 - 5277