(Z)-2-甲基-2-丁烯腈合成路线 （共 29 条）
反应条件
potassium hydroxide; hydrogen in water T=45°C; 1.66667 h; Yield given. Yields of byproduct given;
参考文献
Funabiki, Takuzo; Hosomi, Hiroaki; Yoshida, Satohiro; Tarama, Kimio
Journal of the American Chemical Society, 1982 , vol. 104, # 6 p. 1560 - 1568
反应条件
Escherichia coli SS1001 cells immobilized in alginate beads in water T=35°C; 22 h;
参考文献
Hann, Eugenia C.; Sigmund, Amy E.; Fager, Susan K.; Cooling, Frederick B.; Gavagan, John E.; Bramucci, Michael G.; Chauhan, Sarita; Payne, Mark S.; DiCosimo, Robert
Tetrahedron, 2004 , vol. 60, # 3 p. 577 - 581
反应条件
NiBr2(PPh3)2; triphenylphosphine; zinc in N,N-dimethyl-formamide T=40°C; 8 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Sakakibara, Yasumasa; Enami, Hiroji; Ogawa, Hiroshi; Fujimoto, Shinpei; Kato, Hiroyuki; et al.
Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 11 p. 3137 - 3144
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane T=0 - 20°C; 16 h; Inert atmosphere;
参考文献
Tellew, John E.; Leith, Leslie; Mathur, Arvind
Organic Process Research and Development, 2007 , vol. 11, # 2 p. 275 - 277
反应条件
NiBr2(PPh3)2; triphenylphosphine; zinc in N,N-dimethyl-formamide T=30°C; 8 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Sakakibara, Yasumasa; Enami, Hiroji; Ogawa, Hiroshi; Fujimoto, Shinpei; Kato, Hiroyuki; et al.
Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 11 p. 3137 - 3144
反应条件
NiBr2(PPh3)2; triphenylphosphine; zinc in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=30°C; 8 h; Yield given. Yields of byproduct given;
参考文献
Sakakibara, Yasumasa; Enami, Hiroji; Ogawa, Hiroshi; Fujimoto, Shinpei; Kato, Hiroyuki; et al.
Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 11 p. 3137 - 3144
反应条件
NiBr2(PPh3)2; triphenylphosphine; zinc in N,N-dimethyl-formamide T=50°C; 4 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Sakakibara, Yasumasa; Enami, Hiroji; Ogawa, Hiroshi; Fujimoto, Shinpei; Kato, Hiroyuki; et al.
Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 11 p. 3137 - 3144
反应条件
I basic alumina T=85°C; 18 h; Product distribution / selectivity;
参考文献
E.I. DUPONT DE NEMOURS AND COMPANY
Patent: WO2004/101513 A2, 2004 ;
Location in patent: Page 25 ;
反应条件
1: 98 percent / activity I basic alumina / 18 h / 85 °C 2: Escherichia coli SS1001 cells immobilized in alginate beads / H2O / 22 h / 35 °C View Scheme
参考文献
Hann, Eugenia C.; Sigmund, Amy E.; Fager, Susan K.; Cooling, Frederick B.; Gavagan, John E.; Bramucci, Michael G.; Chauhan, Sarita; Payne, Mark S.; DiCosimo, Robert
Tetrahedron, 2004 , vol. 60, # 3 p. 577 - 581
反应条件
C14H32P2*2H(1-)*2Ni(1+) in decane T=100°C; 3 h; Inert atmosphere; Kinetics; SolventTemperatureReagent/catalyst;
参考文献
Swartz, Brett D.; Reinartz, Nicole M.; Brennessel, William W.; Garcia, Juventino J.; Jones, William D.
Journal of the American Chemical Society, 2008 , vol. 130, # 26 p. 8548 - 8554
