potassium hydroxide; hydroxylamine hydrochloride in methanol; diethylene glycol T=25°C; 2 h;

1: conc. NH3-solution / dimethylformamide 2: 86 percent / POCl3 / dimethylformamide / 4 h / 40 - 45 °C 3: 80 percent / hydroxylamine hydrochloride, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 2 h / 25 °C View Scheme

1: SOCl2 / dimethylformamide / 6 h / Heating 2: conc. NH3-solution / dimethylformamide 3: 86 percent / POCl3 / dimethylformamide / 4 h / 40 - 45 °C 4: 80 percent / hydroxylamine hydrochloride, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 2 h / 25 °C View Scheme

1: 86 percent / POCl3 / dimethylformamide / 4 h / 40 - 45 °C 2: 80 percent / hydroxylamine hydrochloride, KOH / bis-(2-hydroxy-ethyl) ether; methanol / 2 h / 25 °C View Scheme

pyridine 5 h; Heating;

phosphoric acid; sulfuric acid; sodium nitrite T=0°C; 4 h;