3-(三氟甲基)苯基乙酰氯合成路线 （共 4 条）
反应条件
thionyl chloride; N,N-dimethyl-formamide in dichloromethane T=23°C;
参考文献
Chatterjee, Arnab K.; Liu, Hong; Tully, David C.; Guo, Jianhua; Epple, Robert; Russo, Ross; Williams, Jennifer; Roberts, Michael; Tuntland, Tove; Chang, Jonathan; Gordon, Perry; Hollenbeck, Thomas; Tumanut, Christine; Li, Jun; Harris, Jennifer L.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 10 p. 2899 - 2903
反应条件
in dichloromethane; N,N-dimethyl-formamide
参考文献
Cortech, Inc.
Patent: US5618792 A1, 1997 ;
US 5618792 A
反应条件
1: 41 percent / pyridine / benzene / Ambient temperature 2: Irradiation; rate of decarboxylation k(CO2) View Scheme
参考文献
Hilborn, James W.; Pincock, James A.
Canadian Journal of Chemistry, 1992 , vol. 70, # 3 p. 992 - 999
反应条件
1: 2,2-Dimethyl-[1,3]dioxane-4,6-dione; α,α,α-trifluoro-m-tolyl acetyl chloride With N-ethyl-N,N-diisopropylamine in dichloromethane
T=0 - 20°C; 4 h;
2: ethanol 2 h; Heating;
参考文献
Terai, Takuya; Kikuchi, Kazuya; Iwasawa, Shin-Ya; Kawabe, Takao; Hirata, Yasunobu; Urano, Yasuteru; Nagano, Tetsuo
Journal of the American Chemical Society, 2006 , vol. 128, # 21 p. 6938 - 6946
