(4-氟-苯基)-吗啉-4-基-甲酮合成路线 （共 9 条）
反应条件
imidazole hydrochloride in water
T=20°C; 0.166667 h;
参考文献
Verma, Sanjeev K.; Ghorpade, Ramarao; Pratap, Ajay; Kaushik
Tetrahedron Letters, 2012 , vol. 53, # 19 p. 2373 - 2376
反应条件
1: morpholine With C12H30NaO6(1+)*C56H84O4Sm(1-) in tetrahydrofuran
0.5 h; Inert atmosphere;
2: 4-fluorobenzaldehyde in tetrahydrofuran
T=25°C; 3 h; Inert atmosphere;
参考文献
Li, Junmei; Xu, Fan; Zhang, Yong; Shen, Qi
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2575 - 2577
反应条件
potassium carbonate; bis[2-(diphenylphosphino)phenyl] ether in toluene
T=105°C; P=3000.3 Torr; 12 h;
参考文献
Dang, Tuan T.; Zhu, Yinghuai; Ngiam, Joyce S. Y.; Ghosh, Subhash C.; Chen, Anqi; Seayad, Abdul M.
ACS Catalysis, 2013 , vol. 3, # 6 p. 1406 - 1410
反应条件
potassium phosphate; Pd((imidazolium)acetonaphthene)(allyl)Cl in toluene
T=90°C; P=760.051 Torr; 19 h; Schlenk technique;
参考文献
Fang, Weiwei; Deng, Qinyue; Xu, Mizhi; Tu, Tao
Organic Letters, 2013 , vol. 15, # 14 p. 3678 - 3681
反应条件
in thionyl chloride; dichloromethane
T=0 - 20°C; 0.166667 h; Reflux;
参考文献
Melomedov, Jascha; Wuensche Von Leupoldt, Anica; Meister, Michael; Laquai, Frederic; Heinze, Katja
Dalton Transactions, 2013 , vol. 42, # 26 p. 9727 - 9739
反应条件
in tetrahydrofuran; hexane
T=0°C; 0.166667 h; Inert atmosphere;
参考文献
Park, Jae Kyo; Shin, Won Kyu; An, Duk Keun
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 5 p. 1592 - 1594
反应条件
bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; triphenylphosphine in toluene
T=140°C; 20 h;
参考文献
Tillack, Annegret; Rudloff, Ivo; Beller, Matthias
European Journal of Organic Chemistry, 2001 , # 3 p. 523 - 528
反应条件
caesium carbonate in toluene
24 h; RefluxInert atmosphere;
参考文献
Shimizu, Ken-Ichi; Ohshima, Keiichiro; Satsuma, Atsushi
Chemistry - A European Journal, 2009 , vol. 15, # 39 p. 9977 - 9980
反应条件
1: 0.08 h / Neat (no solvent)
2: imidazole hydrochloride / water / 0.17 h / 20 °C
View Scheme
参考文献
Verma, Sanjeev K.; Ghorpade, Ramarao; Pratap, Ajay; Kaushik
Tetrahedron Letters, 2012 , vol. 53, # 19 p. 2373 - 2376
