4-(二甲基氨基)苯-1-磺酰氯合成路线 （共 13 条）
反应条件
phosphorus pentachloride in dichloromethane T=0°C;
参考文献
Binisti, Carine; Assogba, Leon; Touboul, Estera; Mounier, Carine; Huet, Jack; Ombetta, Jean-Edouard; Dong, Chang Zhi; Redeuilh, Catherine; Heymans, Francoise; Godfroid, Jean-Jacques
European Journal of Medicinal Chemistry, 2001 , vol. 36, # 10 p. 809 - 828
反应条件
chlorosulfonic acid; sodium hydrogencarbonate in dichloromethane; chloroform
参考文献
Anacor Pharmaceuticals, Inc.; GlaxoSmithKline
Patent: US2010/256092 A1, 2010 ;
US 20100256092 A1
反应条件
1: With iodine; magnesium in tetrahydrofuran 1 h; Heating; 2: With sulfur dioxide in tetrahydrofuran T=-40°C; 0.5 h; 3: With sulfuryl dichloride in tetrahydrofuran T=-40 - 20°C;
参考文献
Pandya, Rina; Murashima, Takashi; Tedeschi, Livio; Barrett, Anthony G. M.
Journal of Organic Chemistry, 2003 , vol. 68, # 21 p. 8274 - 8276
反应条件
sodium acetate; acetic acid T=25°C; k = 4.95E-3/sec; Rate constant;
参考文献
Sanecki, Przemyslaw; Rokaszewski, Edward
Canadian Journal of Chemistry, 1987 , vol. 65, p. 2263 - 2267
反应条件
aluminium trichloride
参考文献
Horner,L.; Meyer,E.
Justus Liebigs Annalen der Chemie, 1975 , p. 2053 - 2078
参考文献
Sukenik,C.N.; Bergman,R.G.
Journal of the American Chemical Society, 1976 , vol. 98, p. 6613 - 6623
参考文献
Sukenik,C.N.; Bergman,R.G.
Journal of the American Chemical Society, 1976 , vol. 98, p. 6613 - 6623
参考文献
Sukenik,C.N.; Bergman,R.G.
Journal of the American Chemical Society, 1976 , vol. 98, p. 6613 - 6623
参考文献
Sukenik,C.N.; Bergman,R.G.
Journal of the American Chemical Society, 1976 , vol. 98, p. 6613 - 6623
参考文献
Sukenik,C.N.; Bergman,R.G.
Journal of the American Chemical Society, 1976 , vol. 98, p. 6613 - 6623
