2-(3-氯丙基)-1,2,4-噻唑并[4,3-a]吡啶-3(2H)-酮合成路线 （共 2 条）
反应条件
1: 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one With sodium hydride in DMF (N,N-dimethyl-formamide) 0.5 h; 2: 3-chloropropyl tosylate in DMF (N,N-dimethyl-formamide) T=50°C; 4 h;
参考文献
Wyeth
Patent: US2004/204402 A1, 2004 ;
Location in patent: Page/Page column 12-13 ;
US 20040204402 A1
反应条件
potassium carbonate in acetonitrile 8 h; Heating / reflux;
参考文献
Hypnion, Inc.
Patent: US2003/232839 A1, 2003 ;
Location in patent: Page 24; 26 ;
