1-噻吩-2-基-乙酮肟合成路线 （共 27 条）
反应条件
hydroxylamine hydrochloride; sodium carbonate; acetic acid in methanol; water 2 h; Heating;
参考文献
Goda; Sato; Ihara; Hirayama
Synthesis, 1992 , # 9 p. 849 - 851
反应条件
hydrogenchloride T=70°C; 1.5 h;
参考文献
Gordeeva, G. N.; Kalashnikov, S. M.; Popov, Yu. N.; Kruglov, E. A.; Imashev, U. B.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 6 p. 638 - 641
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , vol. 23, # 6 p. 772 - 775
反应条件
hydrogenchloride T=70°C; 1.5 h;
参考文献
Gordeeva, G. N.; Kalashnikov, S. M.; Popov, Yu. N.; Kruglov, E. A.; Imashev, U. B.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 6 p. 638 - 641
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , vol. 23, # 6 p. 772 - 775
反应条件
1: 77 percent / NaOH, NH2OH*HCl / H2O / 48 h / Ambient temperature 2: NaOH / H2O / 7 h / Heating View Scheme
参考文献
Fitton, Alan O.; Patel, Rajeshkumar N.; Millar, Ross W.
Journal of Chemical Research, Miniprint, 1986 , # 4 p. 1101 - 1127
反应条件
boron trifluoride diethyl etherate in methanol
参考文献
Madabhushi, Sridhar; Vangipuram, Venkata Sairam; Mallu, Kishore Kumar Reddy; Chinthala, Narsaiah; Beeram, China Ramanaiah
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 8 p. 1413 - 1416
反应条件
1: acetyl chloride / anschliessend Erhitzen unter vermindertem Druck 2: concentrated aqueous hydrochloric acid View Scheme
参考文献
Steinkopf; Thormann
Justus Liebigs Annalen der Chemie, 1939 , vol. 540, p. 1,5
反应条件
1: 95 percent / NaOH / dimethylformamide; H2O / 0.5 h / 10 °C 2: 75 percent / acetyl nitrate, Ac2O / 3 h / Ambient temperature 3: 98 percent / 25percent HCl / 8 h / 70 °C View Scheme
参考文献
Goda; Sato; Ihara; Hirayama
Synthesis, 1992 , # 9 p. 849 - 851
反应条件
phosphoric acid in water T=95°C; 2 h;
参考文献
Bhar, Sanjay; Guha, Sharmistha
Synthetic Communications, 2005 , vol. 35, # 9 p. 1183 - 1188
反应条件
potassium hydroxide in dimethyl sulfoxide T=20 - 35°C; Etherification; Alkylation; Hydrolysis; 2.5 h; Title compound not separated from byproducts;
参考文献
Tarasova; Shmidt; Sinegovskaya; Petrova; Sobenina; Mikhaleva; Brandsma; Trofimov
Russian Journal of Organic Chemistry, 1999 , vol. 35, # 11 p. 1581 - 1586
反应条件
1: 95 percent / NaOH / dimethylformamide; H2O / 0.5 h / 10 °C 2: 85 percent / Fe, Br2 / CHCl3 / 3 h / Heating 3: 95 percent / 25percent HCl / 8 h / 70 °C View Scheme
参考文献
Goda; Sato; Ihara; Hirayama
Synthesis, 1992 , # 9 p. 849 - 851
