4-氯-beta,beta-二甲基-苯乙烯合成路线 （共 13 条）
反应条件
carbon monoxide; oxygen; copper dichloride; palladium dichloride in tetrahydrofuran Ambient temperature;
参考文献
Botteghi, Carlo; Bona, Denis Dalla; Paganelli, Stefano; Marchetti, Mauro; Sechi, Barbara
Anales de Quimica, 1996 , vol. 92, # 2 p. 101 - 107
反应条件
aluminium trichloride; zinc in acetonitrile
reductive cross coupling; 19 h; Heating;
参考文献
Kumar Dutta; Konwar
Tetrahedron Letters, 2000 , vol. 41, # 32 p. 6227 - 6229
反应条件
sulfuric acid; acetic anhydride
4 h; Heating;
参考文献
Amano; Yoshikawa; Ogawa; Sano; Ohuchi; Tanami; Ota; Hatayama; Higuchi; Amanuma
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 11 p. 4653 - 4662
反应条件
2,6-dimethylpyridine in methanol
参考文献
Bunnett,J.F.; Sridharan,S.
Journal of Organic Chemistry, 1979 , vol. 44, # 9 p. 1458 - 1463
反应条件
1: (i) Mg, (ii) /BRN= 635680/, (iii) SOCl2, Py
2: 2,6-lutidine / methanol
View Scheme
参考文献
Bunnett,J.F.; Sridharan,S.
Journal of Organic Chemistry, 1979 , vol. 44, # 9 p. 1458 - 1463
反应条件
1: 59 percent / tetrahydrofuran / 1 h / 5 - 10 °C
2: 60 percent / acetic anhydride, cc. H2SO4 / 4 h / Heating
View Scheme
参考文献
Amano; Yoshikawa; Ogawa; Sano; Ohuchi; Tanami; Ota; Hatayama; Higuchi; Amanuma
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 11 p. 4653 - 4662
反应条件
ammonium cerium(IV) nitrate; sodium acetate
1.) 100 deg C, 20 h, 2.) acetone, water, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Bly, Robert S.; Ni, Ester K.; Tse, Albert K. K.; Wallace, Easley
Journal of Organic Chemistry, 1980 , vol. 45, # 8 p. 1362 - 1366
反应条件
potassium hydrogensulfate; hydroquinone
参考文献
Yandovskii,V.N.; Temnikova,T.I.
Journal of Organic Chemistry USSR (English Translation), 1968 , vol. 4, p. 973 - 974
Zhurnal Organicheskoi Khimii, 1968 , vol. 4, # 6 p. 1004 - 1006
反应条件
HMDS
1.) THF, r.t., 30 min, 2.) THF, r.t., 20 min; Yield given. Multistep reaction;
参考文献
Bolli, Martin H.; Ley, Steven V.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 15 p. 2243 - 2246
反应条件
sodium amide
1.) THF, 2.) THF; Yield given. Multistep reaction;
参考文献
Botteghi, Carlo; Bona, Denis Dalla; Paganelli, Stefano; Marchetti, Mauro; Sechi, Barbara
Anales de Quimica, 1996 , vol. 92, # 2 p. 101 - 107
