1-甲基-3,5-二苯基-吡唑合成路线 (共 73 条)
反应条件
sulfuric acid in methanol; dichloromethane
参考文献
BASF Aktiengesellschaft
Patent: US5847154 A1, 1998 ;
反应条件
sulfuric acid in methanol
参考文献
BASF Aktiengesellschaft
Patent: US5847154 A1, 1998 ;
反应条件
sulfur trioxide in methanol
参考文献
BASF Aktiengesellschaft
Patent: US5847154 A1, 1998 ;
反应条件
dimethyl sulfate in anhydrous xylene
参考文献
American Cyanamid Co.
Patent: US4162913 A1, 1979 ;
参考文献
American Cyanamid Company
Patent: US4170464 A1, 1979 ;
反应条件
in xylene T=100°C; 6 h;
参考文献
Cross; Arotin; Ruopp
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 5 p. 905 - 910
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; 1 h; Inert atmosphere; regioselective reaction;
参考文献
Tinarelli, Alessandro; Righi, Paolo; Rosini, Goffredo; Andreotti, Daniele; Profeta, Roberto; Spada, Simone
Tetrahedron, 2011 , vol. 67, # 3 p. 612 - 617
反应条件
sodium hydroxide; dimethyl sulfate in water; isobutyl methylketone
参考文献
American Cyanamid Company
Patent: US4014896 A1, 1977 ;
反应条件
pyridine; hydrogenchloride in water; sodium acetate
参考文献
American Cyanamid Company
Patent: US4170464 A1, 1979 ;
反应条件
1: 3,5-Diphenylpyrazole With sodium hydride in tetrahydrofuran
T=20°C; 0.5 h;
2: methyl iodide in tetrahydrofuran
T=20°C; 16 h;
参考文献
Liu, Ping; Xu, Qian-Qian; Dong, Chao; Lei, Xinsheng; Lin, Guo-Qiang
Synlett, 2012 , vol. 23, # 14 p. 2087 - 2092