4-氨基-5-(甲酰氨基甲基)-2-甲基嘧啶合成路线 （共 32 条）
反应条件
copper(l) chloride in pentan-3-one T=88°C; 14 h; Heating / reflux; Product distribution / selectivity;
参考文献
Letinois, Ulla; Schuetz, Jan; Haerter, Ralph; Stoll, Rinke; Huffschmidt, Florian; Bonrath, Werner; Karge, Reinhard
Organic Process Research and Development, 2013 , vol. 17, # 3 p. 427 - 431
反应条件
ammonium hydroxide in water T=42°C; 16 h; Inert atmosphere; Product distribution / selectivity;
参考文献
DSM IP ASSETS B.V.; KARGE, Reinhard; LETINOIS, Ulla; SCHIEFER, Gerhard
Patent: WO2010/10113 A1, 2010 ;
Location in patent: Page/Page column 16-17 ;
反应条件
sodium methylate in methanol; ethanol
参考文献
BASF Aktiengesellschaft
Patent: US4226799 A1, 1980 ;
反应条件
in N2; isopropyl alcohol
参考文献
BASF Aktiengesellschaft
Patent: US4716243 A1, 1987 ;
反应条件
nickel T=130 - 150°C; P=36775.4 - 73550.8 Torr; Hydrogenation;
参考文献
Sekiya
Yakugaku Zasshi, 1950 , vol. 70, p. 520,522,523
Chem.Abstr., 1951 , p. 5640
反应条件
nickel T=130 - 150°C; P=36775.4 - 73550.8 Torr; Hydrogenation;
参考文献
Sekiya
Yakugaku Zasshi, 1950 , vol. 70, p. 520,522,523
Chem.Abstr., 1951 , p. 5640
反应条件
1: POCl3 / folgendes Erhitzen mit aethanol.NH3 2: N2H4+H2O 3: KNO2; water; HCl View Scheme
参考文献
Matsukawa
Yakugaku Zasshi, 1942 , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., 1951 , p. 4724
反应条件
ethanol T=150°C; Hydrogenation;
参考文献
Sekiya
Yakugaku Zasshi, 1950 , vol. 70, p. 520,522,523
Chem.Abstr., 1951 , p. 5640
反应条件
nickel T=150°C; Hydrogenation;
参考文献
Sekiya
Yakugaku Zasshi, 1950 , vol. 70, p. 520,522,523
Chem.Abstr., 1951 , p. 5640
反应条件
1: N2H4+H2O 2: KNO2; water; HCl View Scheme
参考文献
Matsukawa
Yakugaku Zasshi, 1942 , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., 1951 , p. 4724
