2-氨基-6-甲基-4-苯基-3-吡啶甲腈合成路线 （共 9 条）
反应条件
ammonium acetate in 2,2,2-trifluoroethanol
6 h; Reflux;
参考文献
Khaksar, Samad; Yaghoobi, Mandana
Journal of Fluorine Chemistry, 2012 , vol. 142, p. 41 - 44
反应条件
ammonium acetate in ethanol
5 h; Reflux;
参考文献
Said, Said Aly
Monatshefte fur Chemie, 2009 , vol. 140, # 5 p. 573 - 579
反应条件
sodium ethanolate in ethanol
9 h; Ambient temperature;
参考文献
Katoh, Akira; Omote, Yoshimori; Kashima, Choji
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 8 p. 2942 - 2946
反应条件
ammonium acetate in benzene
3 h; Heating;
参考文献
Kambe, Satoshi; Saito, Koji; Sakurai, Akio; Midorikawa, Hiroshi
Synthesis, 1980 , # 5 p. 366 - 368
反应条件
sodium ethanolate in ethanol
9 h; Ambient temperature;
参考文献
Katoh, Akira; Omote, Yoshimori; Kashima, Choji
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 8 p. 2942 - 2946
反应条件
ammonium acetate in ethanol
4 h; Heating;
参考文献
Troschutz; Dennstedt
Archiv der Pharmazie, 1994 , vol. 327, # 1 p. 33 - 40
反应条件
3: hydroxylamine; triethylamine / N,N-dimethyl-formamide; water / 20 °C
View Scheme
参考文献
Xin, Xiaoqing; Huang, Peng; Xiang, Dexuan; Zhang, Rui; Zhao, Fengyu; Zhang, Ning; Dong, Dewen
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 6 p. 1001 - 1006
反应条件
1.1: piperidine / toluene / 12 h / 20 °C / Inert atmosphere
1.2: 6 h / Inert atmosphere
2.1: ammonium acetate; acetic acid / 16 h / Reflux
View Scheme
参考文献
Alvarez-Pere, Monica; Marco-Contelles, Jose
Arkivoc, 2011 , vol. 2011, # 2 p. 283 - 296
反应条件
hydroxylamine hydrochloride; sodium acetate; acetic acid
5 h; Reflux;
参考文献
Said, Said Aly
Monatshefte fur Chemie, 2009 , vol. 140, # 5 p. 573 - 579
