5-氨基-2-甲基苯甲酸甲酯合成路线

77324-87-92-甲基-5-硝基苯甲酸甲酯→18595-12-55-氨基-2-甲基苯甲酸甲酯

参考文献

PHARMACIA and UPJOHN COMPANY
Patent: WO2004/18414 A2, 2004 ;
Location in patent: Page 110 ;

1975-52-62-甲基-5-硝基苯甲酸→18595-12-55-氨基-2-甲基苯甲酸甲酯

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 10 p. 2823 - 2827

18583-89-63-氨基-2-甲基苯甲酸甲酯→83140-97-0+18595-12-55-氨基-2-甲基苯甲酸甲酯

参考文献

US5234946 A1, ;

18595-12-55-氨基-2-甲基苯甲酸甲酯→111437-10-6

参考文献

SIGNAL PHARMACEUTICALS, LLC
Patent: WO2009/89042 A1, 2009 ;
Location in patent: Page/Page column 128 ;
WO 2009/089042 A1

18595-12-55-氨基-2-甲基苯甲酸甲酯→73505-48-35-羟基-2-甲基苯甲酸甲酯

参考文献

Ray, Sutapa; Patra, Asit; Mal, Dipakranjan
Tetrahedron, 2008 , vol. 64, # 14 p. 3253 - 3267

18595-12-55-氨基-2-甲基苯甲酸甲酯→34170-23-56,10-二羟基-1-甲基-苯并(h)(1)苯并吡喃并(5,4,3-cde)(1)苯并吡喃-5,12-二酮

参考文献

Mal, Dipakranjan; Patra, Asit; Roy, Haren
Tetrahedron Letters, 2004 , vol. 45, # 42 p. 7895 - 7898

773837-37-9+18595-12-55-氨基-2-甲基苯甲酸甲酯→103261-68-3

参考文献

THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; PURDUE RESEARCH FOUNDATION
Patent: US2011/269834 A1, 2011 ;
Location in patent: Page/Page column 29 ;

18595-12-55-氨基-2-甲基苯甲酸甲酯+544-92-3氰化亚铜+151-50-8氰化钾→103261-68-3

参考文献

PHARMACIA and UPJOHN COMPANY
Patent: WO2004/18414 A2, 2004 ;
Location in patent: Page 111 ;

18595-12-55-氨基-2-甲基苯甲酸甲酯+544-92-3氰化亚铜→103261-68-3

参考文献

Thorarensen, Atli; Wakefield, Brian D.; Romero, Donna L.; Marotti, Keith R.; Sweeney, Michael T.; Zurenko, Gary E.; Rohrer, Douglas C.; Han, Fusen; Bryant Jr., Garold L.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 10 p. 2823 - 2827

18595-12-55-氨基-2-甲基苯甲酸甲酯→791856-35-42-甲酰基-3-羟基-6-甲基-苯甲酸甲酯

参考文献

Mal, Dipakranjan; Patra, Asit; Roy, Haren
Tetrahedron Letters, 2004 , vol. 45, # 42 p. 7895 - 7898