1-(3-溴-4-羟基苯基)乙酮合成路线 （共 11 条）
反应条件
hydrogen bromide; dihydrogen peroxide in 1,4-dioxane; water 20 h; Heating;
参考文献
Tillu, Vasudha H.; Shinde, Popat D.; Bedekar, Ashutosh V.; Wakharkar, Radhika D.
Synthetic Communications, 2003 , vol. 33, # 8 p. 1399 - 1403
反应条件
aluminium trichloride in carbon disulfide 1.) RT, 1 h, 2.) reflux, 12 h;
参考文献
Leclerc, Gerard; Bizec, Jean Claude; Bieth, Nicole; Schwartz, Jean
Journal of Medicinal Chemistry, 1980 , vol. 23, # 7 p. 738 - 744
反应条件
N-bromosuccinmide; lithium perchlorate; silica gel in dichloromethane T=20°C; 0.0833333 h;
参考文献
Heravi, Majid M.; Abdolhosseini, Nafiseh; Oskooie, Hossein A.
Tetrahedron Letters, 2005 , vol. 46, # 51 p. 8959 - 8963
反应条件
aluminium trichloride T=120°C;
参考文献
Dandegaonker,S.H.; Revankar,G.R.
Monatshefte fuer Chemie, 1965 , vol. 96, p. 450 - 460
反应条件
1: acetic anhydride / Heating 2: AlCl3 / 120 °C View Scheme
参考文献
Dandegaonker,S.H.; Revankar,G.R.
Monatshefte fuer Chemie, 1965 , vol. 96, p. 450 - 460
反应条件
phenyltrimethylammonium tribromide in methanol; chloroform 0.5 h; other reagent, var. solvents; Product distribution;
参考文献
Matsunaga, Yoichiro; Imafuku, Kimiaki
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 1 p. 295 - 297
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate in tetrahydrofuran Suzuki-Miyaura cross-coupling; Inert atmosphereReflux;
参考文献
Wang, Bing; Sun, Hui-Xia; Sun, Zhi-Hua; Lin, Guo-Qiang
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 3 p. 415 - 422
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate in tetrahydrofuran Suzuki coupling; Inert atmosphereReflux; chemoselective reaction;
参考文献
Sun, Hui-Xia; Sun, Zhi-Hua; Wang, Bing
Tetrahedron Letters, 2009 , vol. 50, # 14 p. 1596 - 1599
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate in tetrahydrofuran Suzuki coupling; Inert atmosphereReflux; chemoselective reaction;
参考文献
Sun, Hui-Xia; Sun, Zhi-Hua; Wang, Bing
Tetrahedron Letters, 2009 , vol. 50, # 14 p. 1596 - 1599
反应条件
1: CuSO4‵5H2O; sodium hydroxide / water / 18 h / Reflux 2: 18-crown-6 ether; potassium carbonate / acetone / 6 h / Reflux View Scheme
参考文献
Marshall, Laura J.; Cable, Karl M.; Botting, Nigel P.
Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 5-6 p. 315 - 318
