4-(甲氨基)苯甲酸甲酯合成路线 （共 26 条）
反应条件
toluene-4-sulfonic acid 72 h; Heating;
参考文献
Jones, Paul; Villeneuve, Gerald B.; Fei, Chengpei; DeMarte, Josie; Haggarty, Allison J.; Nwe, Khin Than; Martin, Deborah A.; Lebuis, Anne-Marie; Finkelstein, Joshua M.; Gour-Salin, Barbara J.; Chan, Tak Hang; Leyland-Jones, Brian R.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 16 p. 3062 - 3077
反应条件
potassium carbonate in acetonitrile T=80°C; 16 h;
参考文献
Gray, Vincent James; Wilden, Jonathan D.
Tetrahedron Letters, 2012 , vol. 53, # 1 p. 41 - 44
反应条件
potassium phosphate; triethylamine; tetrakis(triphenylphosphine) palladium(0) in toluene T=110°C; 72 h;
参考文献
Angewandte Chemie - International Edition, , vol. 46, # 38 p. 7270 - 7272
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 1.5 h;
参考文献
US2003/232804 A1, ;
Page 105 ;
反应条件
potassium phosphate; phenol; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=90°C; 36 h;
参考文献
Sole, Daniel; Serrano, Olga
Journal of Organic Chemistry, 2008 , vol. 73, # 6 p. 2476 - 2479
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=20°C;
参考文献
Le Pera, Adolfo; Leggio, Antonella; Liguori, Angelo
Tetrahedron, 2006 , vol. 62, # 25 p. 6100 - 6106
反应条件
triethylsilane; tin(IV) chloride in dichloromethane T=20 - 25°C; Rearrangement; Reduction;
参考文献
Lopez, Francisco J.; Nitzan, Dov
Tetrahedron Letters, 1999 , vol. 40, # 11 p. 2071 - 2074
反应条件
lithium hydroxide in tetrahydrofuran Methylation; esterification; 2 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 64, # 21 p. 8014 - 8017
反应条件
(ethyl)-triphenylphosphonium iodide T=170°C; 0.5 h; Further byproducts given;
参考文献
Selva, Maurizio; Perosa, Alvise; Tundo, Pietro; Brunelli, Davide
Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5770 - 5773
参考文献
Pfizer Inc.
Patent: US6201007 B1, 2001 ;
