1-(3,4-二甲氧基苯基)-1-丙酮合成路线 （共 42 条）
反应条件
1: propionyl chloride With AlCl3, aluminium chloride in dichloromethane T=-10 - 2°C; 2: 1,2-dimethoxy-benzene in dichloromethane T=-4 - 1°C; 3: With hydrogenchloride; water T=-10 - 16°C;
参考文献
Li, Xu; Jiang, Jian-Hong; Chen, Qingqi; Xiao, Sheng-Xiong; Li, Chuan-Hua; Gu, Hui-Wen; Zhang, Hui; Hu, Ji-Lin; Yao, Fei-Hong; Li, Qiang-Guo
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 605 - 613
反应条件
zirconocene dichloride in tetrahydrofuran T=-78 - 20°C; 1.75 h;
参考文献
US2007/49609 A1, ;
Page/Page column 86 ;
US 20070049609 A1
反应条件
(NH4)2S2O8; [{(η5-C5Me5)RhCl}2(μ-Cl)2] in water T=110°C; 3 h; Inert atmosphereSealed tube;
参考文献
Li, Yang; Xue, Dong; Lu, Wei; Wang, Chao; Liu, Zhao-Tie; Xiao, Jianliang
Organic Letters, 2014 , vol. 16, # 1 p. 66 - 69
参考文献
Allah, Hassan M. Faid; Soliman, Raafat
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1745 - 1748
反应条件
formic acid; water; 2,3-dicyano-5,6-dichloro-p-benzoquinone in 1,4-dioxane T=110 - 120°C; 0.266667 h; microwave irradiation;
参考文献
Joshi, Bhupendra P.; Sharma, Anuj; Sinha, Arun K.
Canadian Journal of Chemistry, 2005 , vol. 83, # 10 p. 1826 - 1832
反应条件
pyridinium chlorochromate in dichloromethane 4 h; Ambient temperature;
参考文献
Hill, Kenneth A.; Peterson, Dorothy M.; Damodaran, Kalyani M.; Rao, P. Narasimha
Steroids, 1981 , vol. 37, # 3 p. 327 - 344
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Rudenko, A. P.; Vasil'ev, A. V.
Russian Journal of Organic Chemistry, 1995 , vol. 31, # 10 p. 1360 - 1379
Zhurnal Organicheskoi Khimii, 1995 , vol. 31, # 10 p. 1502 - 1522
反应条件
aluminium trichloride in nitromethane 0 deg C -> reflux;
参考文献
Engler, Thomas A.; Combrink, Keith D.; Ray, James E.
Synthetic Communications, 1989 , vol. 19, # 9-10 p. 1735 - 1744
反应条件
1: aq. KOH / 1 h / 25 °C 2: diethyl ether / 2 h 3: potassium dichromate; aq. sulfuric acid / diethyl ether / 5 h / 25 °C View Scheme
参考文献
Chemical Research in Toxicology, , vol. 9, # 1 p. 109 - 113
反应条件
1: diethyl ether / 2 h 2: potassium dichromate; aq. sulfuric acid / diethyl ether / 5 h / 25 °C View Scheme
参考文献
Chemical Research in Toxicology, , vol. 9, # 1 p. 109 - 113
