1-(金刚烷-1-基)-1-丙醇合成路线 （共 9 条）
反应条件
lithium aluminium tetrahydride in diethyl ether T=20°C; 24 h;
参考文献
Vicha, Robert; Potacek, Milan
Tetrahedron, 2005 , vol. 61, # 1 p. 83 - 88
反应条件
1: ethyl bromide With magnesium in diethyl ether 2: adamantane-1-carbonyl chloride in diethyl ether T=20°C; 48 h; Further stages. Further byproducts.;
参考文献
Vicha, Robert; Necas, Marek; Potacek, Milan
Collection of Czechoslovak Chemical Communications, 2006 , vol. 71, # 5 p. 709 - 722
反应条件
1: in tetrahydrofuran T=20 - 35°C; 1 h; 2: With 10percent aq. H2SO4 in tetrahydrofuran
参考文献
Daicel Chemical Industries, Ltd.
Patent: US6344590 B1, 2002 ;
Location in patent: Example 3 ;
反应条件
copper(l) chloride in diethyl ether 1 h; Heating;
参考文献
Grava, I. Ya.; Polis, Ya. Yu.; Lidak, M. Yu.; Liepin'sh, E. E.; Shatts, V. D.; et al.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, # 4 p. 679 - 686
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 4 p. 778 - 786
反应条件
1.1: 89 percent / SOCl2 / toluene / 8 h / 70 °C 2.1: Mg / diethyl ether 2.2: diethyl ether / 48 h / 20 °C View Scheme
参考文献
Shiner Jr., Vernon J.; Neumann, Thomas E.; Basinger, Bradley B.
Croatica Chemica Acta, 1996 , vol. 69, # 4 p. 1405 - 1420
反应条件
1: 89 percent / LiCl; CuCl; AlCl3 / tetrahydrofuran; diethyl ether / 0.17 h / 10 °C 2: 92 percent / LiAlH4 / diethyl ether / 24 h / 20 °C View Scheme
参考文献
Lauria,F. et al.
Farmaco, Edizione Scientifica, 1967 , vol. 22, p. 681 - 691
反应条件
in trifluoroacetic acid T=55°C; 7 h; other molar ratio; Product distribution;
参考文献
Kovalev, V. A.; Shokova,E. A.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, # 1 p. 98 - 104
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 1 p. 109 - 116
反应条件
sulfuric acid 1) 50 deg C, 3 min, 2) room temperature, 1 h; Yield given. Multistep reaction;
参考文献
Fedorova, O. A.; Kovalev, V. V.; Shokova, E. A.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 9 p. 1792 - 1793
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 9 p. 2027 - 2028
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Fedorova, O. A.; Kovalev, V. V.; Shokova, E. A.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 9 p. 1792 - 1793
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 9 p. 2027 - 2028
