phosphorus; bromine man zersetzt das Reaktionsprodukt mit Wasser;

diethyl ether; bromine Erhitzen des Reaktionsprodukts auf 140-150grad;

1: 30 percent / ammonium hydroxide / 168 h / Ambient temperature 2: 64.6 percent / aq. NaOH / 3.5 h / 0 °C 3: 62 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 1.) 0 deg C, 2.0 h, 2.) room temperature, 15.0 h 4: 1.) N-methylmorpholine, 1-hydroxybenzotriazole, 2.) hydrogen / 2.) palladium black / 1.) DMF, water, room temperature, 20.0 h, 2.) methanol, 2.5 h View Scheme

1: 30 percent / ammonium hydroxide / 168 h / Ambient temperature 2: 64.6 percent / aq. NaOH / 3.5 h / 0 °C 3: 62 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 1.) 0 deg C, 2.0 h, 2.) room temperature, 15.0 h 4: 1.) N-methylmorpholine, 1-hydroxybenzotriazole, 2.) hydrogen / 2.) palladium black / 1.) DMF, water, room temperature, 20.0 h, 2.) methanol, 2.5 h View Scheme

hydrogenchloride T=20°C; 1 h;

Calcium chloride; anhydrous tetramethylammonium chloride in acetonitrile

4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide

ammonium hydroxide 168 h; Ambient temperature;

potassium hydroxide in ethanol 10 h; Heating;

potassium hydroxide; water α-oxypalmitic acid;