1-（1-（4-氯苯基）乙烯基）苯合成路线 （共 36 条）
反应条件
potassium phosphate; Ni(PCy3)2Cl2; water in 1,4-dioxane; toluene T=110°C; Suzuki-Miyaura coupling; 20 h; Inert atmosphere;
参考文献
Sun, Chang-Liang; Yang, Wang; Xiao, Zhou; Wu, Zhen-Hua; Li, Bi-Jie; Guan, Bing-Tao; Shi, Zhang-Jie
Chemistry - A European Journal, 2010 , vol. 16, # 20 p. 5844 - 5847
反应条件
potassium phosphate; [Rh(μ-OAc)(COD)]2; diisopropylamine; cyclooctadiene in toluene T=100°C; 72 h; Inert atmosphere; regioselective reaction;
参考文献
Yu, Jung-Yi; Shimizu, Ryosuke; Kuwano, Ryoichi
Angewandte Chemie - International Edition, 2010 , vol. 49, # 36 p. 6396 - 6399
反应条件
4-Methylpyridine; di-tert-butyl dicarbonate; lithium chloride; palladium dichloride in 1-methyl-pyrrolidin-2-one T=120°C; Heck olefination; 16 h; Title compound not separated from byproducts;
参考文献
Goossen, Lukas J.; Paetzold, Jens; Winkel, Lars
Synlett, 2002 , # 10 p. 1721 - 1723
反应条件
tetrakis(triphenylphosphine) palladium(0); silver(I) acetate; triethylamine in methanol Suzuki-Miyaura reaction; 0.333333 h; Ultrasonic wawes;
参考文献
Singh, Fateh V.; Milagre, Humberto M.S.; Eberlin, Marcos N.; Stefani, Helio A.
Tetrahedron Letters, 2009 , vol. 50, # 20 p. 2312 - 2316
反应条件
sodium acetate; E 105 CA/W 5 percent Pd in 1-methyl-pyrrolidin-2-one T=140°C; Heck reaction; 6 h;
参考文献
Heidenreich, Roland G.; Koehler, Klaus; Krauter, Juergen G. E.; Pietsch, Joerg
Synlett, 2002 , # 7 p. 1118 - 1122
反应条件
bis(dibenzylideneacetone)-palladium(0) in acetonitrile T=40°C; 0.5 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kikukawa, Kiyoshi; Naritomi, Masaki; He, Gong-Xin; Wada, Fumio; Matsuda, Tsutomu
Journal of Organic Chemistry, 1985 , vol. 50, # 3 p. 299 - 301
反应条件
1H-imidazole; dihydrogen peroxide; (5,10,15,20-tetrakis(pentafluorophenyl)porphyrin)MnCl in methanol; dichloromethane T=20°C; 24 h; Further byproducts given;
参考文献
Froehlich; Pietzyk; Smolinka; Goeber
Pharmazie, 1996 , vol. 51, # 6 p. 409 - 414
反应条件
1: Pd(dba)2 / acetonitrile / 0.5 h / 40 °C 2: Pd(dba)2 / acetonitrile / 0.5 h / 40 °C View Scheme
参考文献
Kikukawa, Kiyoshi; Naritomi, Masaki; He, Gong-Xin; Wada, Fumio; Matsuda, Tsutomu
Journal of Organic Chemistry, 1985 , vol. 50, # 3 p. 299 - 301
参考文献
Gollnick, Klaus; Schnatterer, Albert; Utschick, Gerald
Journal of Organic Chemistry, 1993 , vol. 58, # 22 p. 6049 - 6056
反应条件
1: pyridine / dichloromethane / 12 h / 0 - 20 °C / |Schlenk technique; |Inert atmosphere 2: bis(dibenzylideneacetone)-palladium(0); 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; dnpf / tetrahydrofuran / 18 h / 80 °C / |Inert atmosphere View Scheme
参考文献
Zou, Yinjun; Qin, Liena; Ren, Xinfeng; Lu, Yunpeng; Li, Yongxin; Zhou, Jianrong
Chemistry - A European Journal, 2013 , vol. 19, # 10 p. 3504 - 3511
