copper(l) iodide; caesium carbonate; N-methyl-2-(methylamino)ethylamine in tetrahydrofuran T=80°C; 16 h; Inert atmosphere;

copper(l) iodide; caesium carbonate; N-methyl-2-(methylamino)ethylamine in tetrahydrofuran T=80°C; 16 h; Inert atmosphere;

1.1: NaI / acetone / Heating 2.1: n-BuLi; i-Pr2NH / hexane; tetrahydrofuran / 1 h / -78 °C 2.2: tetrahydrofuran; hexane / -78 - 20 °C 3.1: 69 percent Spectr. / PPh3; Et3N / Pd(OAc)2 / dimethylformamide; H2O / 24 h / 130 °C View Scheme

copper(l) iodide; caesium carbonate; N-methyl-2-(methylamino)ethylamine in tetrahydrofuran T=80°C; 16 h; Inert atmosphere;