Ce(OTf)4; diethylazodicarboxylate in acetonitrile T=20°C; 12 h; Molecular sieve;

pyridine T=50°C;

triethylamine 0.05 h; Microwave irradiationneat (no solvent);

Ce(OTf)4; diethylazodicarboxylate in acetonitrile T=20°C; 10 h;

暂无反应条件数据

1: 9.9 g / sodium periodate / methanol; H2O / 20 h / Ambient temperature 2: 87 percent / NaBH4 / ethanol / 2 h / Ambient temperature 3: 77 percent / pyridine / 24 h / Ambient temperature 4: 73 percent / 80percent acetic acid / 6 h / 65 °C 5: 93 percent / imidazole / dimethylformamide / 3.5 h / Ambient temperature 6: 59 percent / t-BuOK / 2-methyl-propan-2-ol / 2.5 h / 60 °C View Scheme

1: 9.9 g / sodium periodate / methanol; H2O / 20 h / Ambient temperature 2: 87 percent / NaBH4 / ethanol / 2 h / Ambient temperature 3: 22 percent / pyridine / 6 h 4: 75 percent / 1 N sodium methoxide / methanol / 2.5 h / 60 °C 5: 91 percent / 80percent acetic acid / 4 h / 60 °C View Scheme

ammonium cerium(IV) nitrate; silica gel in dichloromethane T=25°C; detritylation; 1.5 h;

pyridine anschliessendes Erwaermen mit wss.Essigsaeure;

pyridine Erwaermen des Reaktionsprodukts mit wss.Essigsaeure und anschliessend Hydrieren an Palladium/Kohle in H2O.;