potassium fluoride; copper(l) iodide; palladium diacetate; di-(1-adamantyl)-n-butylphosphine in N,N-dimethyl-formamide T=90°C; Hiyama coupling; 12 h; Inert atmosphere;

potassium fluoride; copper(l) iodide; palladium diacetate; di-(1-adamantyl)-n-butylphosphine in N,N-dimethyl-formamide T=90°C; Hiyama coupling; 12 h; Inert atmosphere;

1: 2-bromo-pyridine With tert.-butyl lithium in tetrahydrofuran; pentane T=-78°C; 2: With zinc(II) chloride in tetrahydrofuran; pentane T=20°C; 3: 2-chloropyridine-5-carbonitrile With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tri-tert-butyl phosphine in tetrahydrofuran; pentane 16 h; Heating;

N,N,N',N,-tetramethylethylenediamine; 1,5-bis-(diphenylphosphino)-pentane; Neutral lead acetate in 1,3,5-trimethyl-benzene 16 h; Heating;