4-羟基-3-苯基香豆素合成路线 （共 31 条）
参考文献
Stadlbauer; Ghobrial; Kappe
1980 , vol. 35, # 7 p. 892 - 895
反应条件
pyridine; potassium hydroxide
Dieckmann type cyclization;
参考文献
Taksande, Kiran; Borse; Lokhande, Pradeep
Synthetic Communications, 2010 , vol. 40, # 15 p. 2284 - 2290
反应条件
lithium hydroxide; tri-tert-butyl phosphine; palladium diacetate in ethylene glycol dimethyl ether; water
T=25°C; Suzuki coupling reaction; 14 h;
参考文献
Zhu, Qiang; Wu, Jie; Fathi, Reza; Yang, Zhen
Organic Letters, 2002 , vol. 4, # 19 p. 3333 - 3336
反应条件
dirhodium tetraacetate in hexafluorobenzene
T=130°C; 3 h;
参考文献
Goldoni, Luca; Cravotto, Giancarlo; Penoni, Andrea; Tollari, Stefano; Palmisano, Giovanni
Synlett, 2005 , # 6 art. no. G03605ST, p. 927 - 930
反应条件
sodium ditelluride in tetrahydrofuran
T=-20 - 20°C;
参考文献
Dittmer, Donald C.; Li, Qun; Avilov, Dimitry V.
Journal of Organic Chemistry, 2005 , vol. 70, # 12 p. 4682 - 4686
反应条件
potassium carbonate in acetone
40 h; Heating;
参考文献
Gandhidasan, R.; Neelakantan, S.; Raman, P. V.; Sripathi, Subashini K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 849
反应条件
trifluoroacetic acid in toluene
1 h; Heating;
参考文献
Kalinin, Alexey V.; Da Silva, Alcides J. M.; Lopes, Claudio C.; Lopes, Rosangela S. C.; Snieckus, Victor
Tetrahedron Letters, 1998 , vol. 39, # 28 p. 4995 - 4998
反应条件
1.1: Na2CO3 / H2O / 0.5 h / 20 °C
1.2: Na2CO3 / H2O / 2 h / 20 °C
2.1: 72 percent / LiOH*H2O; P(t-Bu)3 / Pd(OAc)2 / 1,2-dimethoxy-ethane; H2O / 14 h / 25 °C
View Scheme
参考文献
Zhu, Qiang; Wu, Jie; Fathi, Reza; Yang, Zhen
Organic Letters, 2002 , vol. 4, # 19 p. 3333 - 3336
反应条件
2-(tert-butyl)-1,1,3,3-tetramethylguanidine in tetrahydrofuran
23 h; Ambient temperature;
参考文献
Barton; Donnelly; Finet; Stenson
Tetrahedron, 1988 , vol. 44, # 20 p. 6387 - 6396
反应条件
sodium hexamethyldisilazane in tetrahydrofuran
T=-20°C;
参考文献
Dittmer, Donald C.; Li, Qun; Avilov, Dimitry V.
Journal of Organic Chemistry, 2005 , vol. 70, # 12 p. 4682 - 4686
