3-羟基-7-溴-2-萘甲酸合成路线 （共 9 条）
反应条件
hydrogenchloride; tin in acetic acid T=125°C; 12 h; Reflux;
参考文献
Institute Of Pharmacology And Toxicology Academy Of Militaty Medical Sciences P.L.A.; LI, Song; ZHONG, Wu; LIU, Ping; XIAO, Junhai; ZHENG, Zhibing; XIE, Yunde; ZHAO, Guoming; WANG, Xiaokui; WANG, Lili; LI, Xingzhou; ZHOU, Xinbo
Patent: EP2573067 A1, 2013 ;
Location in patent: Paragraph 0053; 0054 ;
反应条件
1: With bromine; acetic acid 2: With hydrogenchloride; tin; acetic acid Heating;
参考文献
Bioorganic and medicinal chemistry letters, , vol. 12, # 15 p. 1941 - 1946
反应条件
1: triethylaluminum 2: bromine; acetic acid 3: tin; acetic acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 132, # 49 p. 17352 - 17353
反应条件
sodium carbonate in water; acetonitrile T=30°C; pH=9.0; 1 h; UV-irradiation;
参考文献
Journal of Organic Chemistry, , vol. 74, # 3 p. 1034 - 1041
反应条件
in acetonitrile T=30°C; 1 h; UV-irradiation;
参考文献
Journal of Organic Chemistry, , vol. 74, # 3 p. 1034 - 1041
反应条件
sulfuric acid 16 h; Heating / reflux;
参考文献
ELI LILLY AND COMPANY
Patent: EP1266897 A2, 2002 ;
Location in patent: Page 61 ;
反应条件
sulfuric acid in ethanol; water
参考文献
Eli Lilly and Company
Patent: US6410562 B1, 2002 ;
参考文献
Chem.Fabr.Griesheim-Elektron
Patent: DE396519 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 1021
反应条件
ammonium hydroxide; sodium hydroxide; copper
T=140°C;
参考文献
I.G. Farbenind.
Patent: DE642380 , 1935 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 23, p. 264
