2,4,4-三甲基-2-恶唑合成路线 （共 40 条）
反应条件
1: tert-butyl hypochlorite 2: 84 percent / lithium diisopropyl amide / tetrahydrofuran / -100 °C 3: 1percent NaOH / propan-2-ol View Scheme
参考文献
Florio, Saverio; Capriati, Vito; Luisi, Renzo
Tetrahedron Letters, 1996 , vol. 37, # 27 p. 4781 - 4784
反应条件
KNH2 1) liq. NH3, -33 deg C, 15 min; 2) irradiation, 5 min, liq. NH3, -33 deg C; further reagents and conditions; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Wong, Jim-Wah; Natalie Jr., Kenneth J.; Nwokogu, Godson C.; Pisipati, Jyothi S.; Flaherty, Patrick T.; Greenwood, Thomas D.; Wolfe, James F.
Journal of Organic Chemistry, 1997 , vol. 62, # 18 p. 6152 - 6159
反应条件
(i) nBuLi, (ii) /BRN= 1718733/, H2SO4; Multistep reaction;
参考文献
Meyers,A.I. et al.
Journal of Organic Chemistry, 1974 , vol. 39, p. 2778 - 2783
反应条件
KNH2 1) liq. NH3, -33 deg C, 15 min; 2) irradiation, 5 min, liq. NH3, -33 deg C; further conditions; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Wong, Jim-Wah; Natalie Jr., Kenneth J.; Nwokogu, Godson C.; Pisipati, Jyothi S.; Flaherty, Patrick T.; Greenwood, Thomas D.; Wolfe, James F.
Journal of Organic Chemistry, 1997 , vol. 62, # 18 p. 6152 - 6159
反应条件
(i) nBuLi, (ii) /BRN= 635704/, (iii) aq. HCl; Multistep reaction;
参考文献
Meyers,A.I. et al.
Journal of Organic Chemistry, 1974 , vol. 39, p. 2778 - 2783
反应条件
(i) nBuLi, (ii) /BRN= 1699049/, (iii) /BRN= 1718733/, H2SO4; Multistep reaction;
参考文献
Meyers,A.I. et al.
Journal of Organic Chemistry, 1974 , vol. 39, p. 2778 - 2783
反应条件
1: nitromethane 2: 70 percent / NaH / tetrahydrofuran / 3 h / 20 °C View Scheme
参考文献
Zhou, Aihua; Pittman Jr., Charles U.
Synthesis, 2006 , # 1 art. no. M01705SS, p. 37 - 48
反应条件
1: tert-butyl hypochlorite 2: 86 percent / lithium diisopropyl amide / tetrahydrofuran / -100 °C 3: 1percent NaOH / propan-2-ol View Scheme
参考文献
Florio, Saverio; Capriati, Vito; Luisi, Renzo
Tetrahedron Letters, 1996 , vol. 37, # 27 p. 4781 - 4784
反应条件
(i) nBuLi, (ii) /BRN= 1098260/, (iii) /BRN= 1718733/, H2SO4; Multistep reaction;
参考文献
Meyers,A.I. et al.
Journal of Organic Chemistry, 1974 , vol. 39, p. 2778 - 2783
反应条件
(i) nBuLi, (ii) /BRN= 385735/, (iii) /BRN= 1718733/, H2SO4; Multistep reaction;
参考文献
Meyers,A.I. et al.
Journal of Organic Chemistry, 1974 , vol. 39, p. 2778 - 2783
