1,4-二氧螺环[4,5]癸烷合成路线 （共 57 条）
反应条件
trimethylsilyl trifluoromethanesulfonate in dichloromethane
T=-78°C; 4 h;
参考文献
Noyori, R.; Murata, S.; Suzuki, M.
Tetrahedron, 1981 , vol. 37, # 23 p. 3899 - 3910
反应条件
zeolite HSZ-360 in toluene
3 h; Heating;
参考文献
Ballini, Roberto; Bosica, Giovanna; Frullanti, Bettina; Maggi, Raimondo; Sartori, Giovanni; Schroer, Frank
Tetrahedron Letters, 1998 , vol. 39, # 12 p. 1615 - 1618
反应条件
triethylsilane; palladium dichloride; tri-cyclo-hexyl-phosphine in tetrahydrofuran
T=20°C; 1 h;
参考文献
Benohoud, Meryem; Tuokko, Sakari; Pihko, Petri M.
Chemistry - A European Journal, 2011 , vol. 17, # 30 p. 8404 - 8413
反应条件
1: 70 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C
2: conc. aq. HCl / tetrahydrofuran / 0.5 h / Ambient temperature
View Scheme
参考文献
Kita, Yasuyuki; Yasuda, Hitoshi; Haruta, Jun-ichi; Segawa, Jun; Tamura, Yasumitsu
Synthesis, 1982 , # 12 p. 1089 - 1091
反应条件
in ethylene glycol
10 h; Irradiation;
参考文献
Kropp, Paul J.; McNeely, Steven A.; Davis, Robert Drummond
Journal of the American Chemical Society, 1983 , vol. 105, # 23 p. 6907 - 6915
反应条件
EM-3993 in acetonitrile
Irradiation;
参考文献
Gassman, Paul G.; Burns, Stephen J.
Journal of Organic Chemistry, 1988 , vol. 53, # 23 p. 5576 - 5578
反应条件
T=40°C; 6 h; Irradiation;
参考文献
Kropp, Paul J.; McNeely, Steven A.; Davis, Robert Drummond
Journal of the American Chemical Society, 1983 , vol. 105, # 23 p. 6907 - 6915
反应条件
lt;Pd(H2O)2(Ph2PCH2CH2PPh2)gt;(CF3SO3)2 in dichloromethane
8 h; Ambient temperature;
参考文献
Gorla, Fabrizio; Venanzi, Luigi M.
Helvetica Chimica Acta, 1990 , vol. 73, # 3 p. 690 - 697
反应条件
[RhCl(η2:η2-cycloocta-1,5-diene)]2; 1,3-bis-(diphenylphosphino)propane in anhydrous xylene
T=130°C; 1 h; Inert atmosphere;
参考文献
Ikeda, Keiichi; Morimoto, Tsumoru; Tsumagari, Takayuki; Tanimoto, Hiroki; Nishiyama, Yasuhiro; Kakiuchi, Kiyomi
Synlett, 2012 , # 3 p. 393 - 396
反应条件
1: CH2Cl2 / 0 °C
2: 48 percent Chromat. / LiAlH4 / Ambient temperature
View Scheme
参考文献
Leone, Christina L.; Chamberlin, A. Richard
Tetrahedron Letters, 1991 , vol. 32, # 14 p. 1691 - 1694
