6-甲氧基-2-苯基四氢萘酮合成路线 （共 24 条）
反应条件
sodium t-butanolate; PdCl2(Amphos)2 in 1,4-dioxane T=100°C; 18 h; Inert atmosphere;
参考文献
WO2012/159981 A2, ;
Page/Page column 20 ;
反应条件
sodium t-butanolate; PdCl2(Amphos)2 in toluene T=60°C; 18 h; Inert atmosphere; Product distribution / selectivity;
参考文献
WO2012/159981 A2, ;
Page/Page column 19-20 ;
反应条件
palladium diacetate; tri-n-butyltin methoxide; tris-(o-tolyl)phosphine in toluene T=100°C;
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 8 p. 1704 - 1719
反应条件
potassium tert-butylate in tetrahydrofuran T=50°C; 15 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 22 p. 3775 - 3778
反应条件
1: p-TSA 2: 49 percent / tri-n-butyltin methoxide, Pd(AcO)2, tri-o-tolylphosphine / toluene / 100 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 8 p. 1704 - 1719
反应条件
2: KOH / ethane-1,2-diol 4: 45 percent View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 107 - 117
反应条件
1: KOH / ethane-1,2-diol 3: 45 percent View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 107 - 117
反应条件
2: KOH / ethane-1,2-diol 4: 45 percent View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 107 - 117
反应条件
1: AcOH / aq. ethanol 2: aq. H2SO4 3: (i) Zn-Hg, aq. HCl, (ii) HF View Scheme
参考文献
Journal of medicinal chemistry, , vol. 9, # 2 p. 172 - 176
反应条件
1: (i) aq. NaOH, EtOH, (ii) /BRN= 471223/ 2: AcOH / aq. ethanol 3: aq. H2SO4 4: (i) Zn-Hg, aq. HCl, (ii) HF View Scheme
参考文献
Journal of medicinal chemistry, , vol. 9, # 2 p. 172 - 176
