反应条件
1: tetrahydrofuran; toluene / 7 h / 45 °C 2: 1.) NEt3 / 1.) CHCl3; 2.) CHCl3, THF, 4 h, -70 deg C then 1 h, room temp. 3: toluene / 20 h / Heating 4: 83 percent / CH2Cl2 / 3.5 h / Ambient temperature 5: 1.) 1.37 M n-BuLi / 1.) hexane, THF, 20 min, -70 deg C; 2.) hexane, THF, 12 h, -70 deg C 6: 0.25 N aq. HCl / 48 h / Ambient temperature View Scheme
