5-溴-3-溴甲基苯并[b]噻吩合成路线 （共 9 条）
反应条件
N-bromosuccinmide in tetrachloromethane
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane 2.5 h; HeatingIrradiation;
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, # 4 p. 1069 - 1071
反应条件
1: 71 percent / phosphorus pentoxide; polyphosphoric acid / 3 h / 180 °C 2: 56 percent / dibenzoyl peroxide; N-bromosuccinimide / CCl4 / 4 h / Irradiation; reflux View Scheme
参考文献
Pharmacy and Pharmacology Communications, , vol. 6, # 2 p. 61 - 65
反应条件
N-bromosuccinmide; dibenzoyl peroxide Irradiation;
参考文献
Magnetic Resonance in Chemistry, , vol. 23, # 10 p. 814 - 821
反应条件
N-bromosuccinmide; dibenzoyl peroxide Irradiation;
参考文献
Magnetic Resonance in Chemistry, , vol. 23, # 10 p. 814 - 821
反应条件
1: 95 percent / Pyridine / diethyl ether / 1 h / Ambient temperature 2: 92 percent / Polyphosphoric acid on Celite / toluene / 24 h / Heating 3: 75 percent / Benzoyl peroxide, N-bromosuccinimide / CCl4 / 2.5 h / Heating; Irradiation View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, # 4 p. 1069 - 1071
反应条件
N-bromosuccinmide; dibenzoyl peroxide Irradiation;
参考文献
Magnetic Resonance in Chemistry, , vol. 23, # 10 p. 814 - 821
反应条件
in ethanol; dichloromethane; water; ethyl acetate
参考文献
ELI LILLY AND COMPANY
Patent: EP835869 A2, 1998 ;
反应条件
in dimethyl sulfoxide T=60°C; 1 h;
参考文献
Leclerc; Beaurain; Depreux; Bennejean; Delagrange; Boutin; Lesieur
Pharmacy and Pharmacology Communications, 2000 , vol. 6, # 2 p. 61 - 65
