3,5-二氯-4-羟基苯甲酸乙酯合成路线 （共 13 条）
参考文献
Gazzetta Chimica Italiana, , vol. 29 I, p. 387,388
反应条件
sulfuric acid 6 h; Reflux;
参考文献
Crystal Growth and Design, , vol. 12, # 11 p. 5411 - 5425
参考文献
Tarbell; Wilson
Journal of the American Chemical Society, 1942 , vol. 64, p. 1066,1069
Full Text Show Details
Tarbell; Wilson; Fanta
Org. Synth. Coll. Vol., 1955 , vol. III, p. 267,268
反应条件
hydrazine hydrate in ethanol 18 h; Reflux;
参考文献
Institute for OneWorld Health
Patent: US2010/267725 A1, 2010 ;
Location in patent: Page/Page column 24 ;
US 20100267725 A1
反应条件
1: aq.-ethanolic KOH-solution View Scheme
参考文献
Tarbell; Wilson
Journal of the American Chemical Society, 1942 , vol. 64, p. 1066,1069
反应条件
1: 3,5-dichloro-4-hydroxy-benzoic acid ethyl ester With potassium carbonate in N,N-dimethyl-formamide T=20°C; Inert atmosphere; 2: methyl iodide in N,N-dimethyl-formamide T=20°C; Inert atmosphere;
参考文献
Grimster, Neil P.; Connelly, Stephen; Baranczak, Aleksandra; Dong, Jiajia; Krasnova, Larissa B.; Sharpless, K. Barry; Powers, Evan T.; Wilson, Ian A.; Kelly, Jeffery W.
Journal of the American Chemical Society, 2013 , vol. 135, # 15 p. 5656 - 5668
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / |Inert atmosphere 1.2: 20 °C / |Inert atmosphere 2.1: hydrazine hydrate / methanol / 2 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Grimster, Neil P.; Connelly, Stephen; Baranczak, Aleksandra; Dong, Jiajia; Krasnova, Larissa B.; Sharpless, K. Barry; Powers, Evan T.; Wilson, Ian A.; Kelly, Jeffery W.
Journal of the American Chemical Society, 2013 , vol. 135, # 15 p. 5656 - 5668
反应条件
anschliessend Erwaermen mit Dimethylsulfat;
参考文献
Bradsher et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 1468
参考文献
Rosales, Carmen Almansa; Gonzalez Gonzalez, Concepcion; Torres Barreda, Maria Carmen
Patent: US2003/176481 A1, 2003 ;
反应条件
1: pyridine
2: LiAlH4; diethyl ether
3: toluene-4-sulfonic acid; benzene
4: sodium; liquid NH3
View Scheme
参考文献
Yamasaki
Kogyo Kagaku Zasshi, 1955 , vol. 58, p. 972
Chem.Abstr., 1956 , p. 12927
