1-(3-氯丙氧基)-4-氟苯合成路线 （共 6 条）
反应条件
potassium carbonate in acetone 24 h; Heating;
参考文献
Walsh, David A.; Franzyshen, Stephen K.; Yanni, John M.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 1 p. 105 - 118
反应条件
nickel in tetrahydrofuran 15 h; Heating;
参考文献
Barrero; Alvarez-Manzaneda; Chahboun; Meneses; Romera
Synlett, 2001 , # 4 p. 485 - 488
反应条件
potassium cyanide; ethanol Erwaermen des Reaktionsprodukts mit wss.-aethanol. Kalilauge;
参考文献
Mel'nikow; Kukalenko
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 3708; engl. Ausg. S. 3664
反应条件
1: 3.4 g / dimethylformamide / 18 h / 80 °C 2: 93 percent / 85percent hydrazine hydrate / ethanol / 3 h / Heating View Scheme
参考文献
Ismaiel; De los Angeles; Teitler; Ingher; Glennon
Journal of Medicinal Chemistry, 1993 , vol. 36, # 17 p. 2519 - 2525
反应条件
in toluene
T=85°C; 2 h;
参考文献
Capuano, Ben; Crosby, Ian T.; McRobb, Fiona M.; Podloucka, Anna; Taylor, David A.; Vom, Amelia; Yuriev, Elizabeth
Australian Journal of Chemistry, 2010 , vol. 63, # 1 p. 116 - 124
反应条件
diisopropylamine in N,N-dimethyl-formamide
T=80°C; 17 h; Inert atmosphere;
参考文献
Zigelboim, Isaac; Weissberg, Avi; Cohen, Yoram
Journal of Organic Chemistry, 2013 , vol. 78, # 14 p. 7001 - 7012
