4-(3,5-二甲氧基苯基)-4-氧代丁酸合成路线 （共 7 条）
反应条件
1: Na / Heating 2: (i) NaOMe, Et2O, (ii) /BRN= 506456/, Et2O, (iii) aq. H2SO4 View Scheme
参考文献
Helvetica Chimica Acta, , vol. 46, p. 2543 - 2551
反应条件
1: aq. NH4Cl, aq. NH3 2: (i) NaOMe, Et2O, (ii) /BRN= 506456/, Et2O, (iii) aq. H2SO4 View Scheme
参考文献
Helvetica Chimica Acta, , vol. 46, p. 2543 - 2551
反应条件
1: (i) Mg(OEt)2, EtOH, Et2O, (ii) /BRN= 511839/ 2: aq. NH4Cl, aq. NH3 3: (i) NaOMe, Et2O, (ii) /BRN= 506456/, Et2O, (iii) aq. H2SO4 View Scheme
参考文献
Helvetica Chimica Acta, , vol. 46, p. 2543 - 2551
参考文献
Yakugaku Zasshi, , vol. 61, p. 283,286
反应条件
(i) NaOMe, Et2O, (ii) /BRN= 506456/, Et2O, (iii) aq. H2SO4; Multistep reaction;
参考文献
Helvetica Chimica Acta, , vol. 46, p. 2543 - 2551
参考文献
Hardegger,E. et al.
Helvetica Chimica Acta, 1963 , vol. 46, p. 2543 - 2551
反应条件
1: polyphosphoric acid / 145 °C
2: NaOMe / benzene
3: (i) Et3N, benzene, (ii) KOH, MeOH
4: p-cymene / Pd-C / Heating
5: K2CO3 / acetone / Heating
View Scheme
参考文献
Hardegger,E. et al.
Helvetica Chimica Acta, 1963 , vol. 46, p. 2543 - 2551
