2-甲基-3-氧代丁酸甲酯合成路线 （共 38 条）
反应条件
potassium carbonate in methanol 3 h; Heating;
参考文献
Lee, Mijoon; Kim, Dong H.
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 4 p. 913 - 922
反应条件
hydrogenchloride in water Reflux;
参考文献
Cuetos, Anibal; Lavandera, Ivan; Gotor, Vicente
Chemical Communications, 2013 , vol. 49, # 91 p. 10688 - 10690
反应条件
palladium(II) 2,4-pentanedionate; tributyl-amine; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene T=90°C; P=7500.75 Torr; 15 h; Inert atmosphereAutoclaveSchlenk technique;
参考文献
Wahl, Benoit; Bonin, Helene; Mortreux, Andre; Sauthier, Mathieu; Giboulot, Steven; Liron, Frederic; Poli, Giovanni
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 16 p. 3105 - 3114,10
反应条件
1: acetoacetic acid methyl ester With sodium hydride in tetrahydrofuran; mineral oil T=20°C; Inert atmosphere; 2: methyl halide in tetrahydrofuran; mineral oil T=40°C; 10 h; Inert atmosphere;
参考文献
Journal of the American Chemical Society, , vol. 133, # 23 p. 8834 - 8837
反应条件
tetra-n-butylammonium tetrafluoroborate; zinc dibromide; zinc in acetonitrile Ambient temperature;
参考文献
Rollin, Y.; Gebehenne, C.; Derien, S.; Dunach, E.; Perichon, J.
Journal of Organometallic Chemistry, 1993 , vol. 461, # 1-2 p. 9 - 14
反应条件
sodium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=20°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Chemische Berichte, , vol. 114, # 8 p. 2866 - 2883
反应条件
Jones reagent in acetone
参考文献
Tetrahedron, , vol. 49, # 48 p. 11169 - 11182
反应条件
potassium carbonate T=0°C; 2.16667 h; Title compound not separated from byproducts;
参考文献
Australian Journal of Chemistry, , vol. 43, # 3 p. 617 - 622
反应条件
hydrogenchloride; tetra-n-butylammonium tetrafluoroborate; zinc dibromide; zinc 1.) RT; Yield given. Multistep reaction;
参考文献
Journal of Organometallic Chemistry, , vol. 444, # 1.2. p. 1 - 4
反应条件
methanol; sodium Umsetzung des Reaktionsprodukts mit Dimethylsulfat in siedendem Benzol;
