1-溴-2,6-二甲氧基苯合成路线 （共 37 条）
反应条件
in acetic acid Ambient temperaturecompetitive bromination with p-dimethoxybenzene;
参考文献
Tetrahedron, , vol. 38, # 8 p. 1105 - 1112
反应条件
N-bromosuccinmide in acetonitrile T=20°C; 15 h; Cooling with ice;
参考文献
Idemitsu Kosan Co., Ltd.
Patent: EP2436679 A1, 2012 ;
Location in patent: Page/Page column 46 ;
反应条件
n-butyllithium in hexane; pentane T=20°C;
参考文献
Journal of the American Chemical Society, , vol. 135, # 3 p. 1026 - 1036
参考文献
Wu, Anhui; Xu, Daiwang; Lu, Ding; Penning, Trevor M.; Blair, Ian A.; Harvey, Ronald G.
Tetrahedron, 2012 , vol. 68, # 35 p. 7217 - 7233
反应条件
1: CuO, collidine 2: Na, aq. NH3 / diethyl ether View Scheme
参考文献
Cannon,J.R. et al.
Australian Journal of Chemistry, 1973 , vol. 26, p. 2257 - 2275
反应条件
1: boron tribromide 2: Basic conditions 3: potassium phosphate; biphenyl-4-yl(di-tert-butylphosphine); palladium diacetate / tetrahydrofuran / 40 °C 4: 10 palladium on activated charcoal; hydrogen 5: pyridine 6: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; diisopropylamine / N,N-dimethyl-formamide 7: methanol; potassium carbonate / tetrahydrofuran 8: platinum (II) chloride 9: boron tribromide View Scheme
参考文献
Wu, Anhui; Xu, Daiwang; Lu, Ding; Penning, Trevor M.; Blair, Ian A.; Harvey, Ronald G.
Tetrahedron, 2012 , vol. 68, # 35 p. 7217 - 7233
反应条件
barium dihydroxide; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane; water 2 h; Heating;
参考文献
Kamikawa, Takashi; Hayashi, Tamio
Tetrahedron, 1999 , vol. 55, # 11 p. 3455 - 3466
反应条件
Yield given. Multistep reaction;
参考文献
Luening, Ulrich; Mueller, Michael
Chemische Berichte, 1990 , vol. 123, p. 643 - 646
反应条件
titanium tetrachloride 1.) CH2Cl2, -40 deg C, 2.) 0 deg C; Yield given. Multistep reaction;
参考文献
Kaliakoudas, Dimitrios; Eugster, Conrad Hans; Rueedi, Peter
Helvetica Chimica Acta, 1990 , vol. 73, # 1 p. 48 - 62
反应条件
carbon dioxide; zinc; palladium on activated charcoal in water
T=20°C; Ullmann coupling; P=7500.6 Torr; 72 h;
参考文献
Li, Jin-Heng; Xie, Ye-Xiang; Yin, Du-Lin
Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9867 - 9869
