3-叔丁基-4-羟基苯乙酮合成路线 （共 5 条）
反应条件
N-bromosuccinmide in acetonitrile T=0°C;
参考文献
Eisai Co., Ltd.
Patent: EP1602646 A1, 2005 ;
Location in patent: Page/Page column 45 ;
反应条件
N-bromosuccinmide; sodium thiosulfate in water; acetonitrile
参考文献
Eisai RandD Management Co., Ltd.
Patent: EP2241315 A1, 2010 ;
反应条件
AlCl3, aluminium chloride in toluene
T=-45°C; 4.5 h;
参考文献
Eisai RandD Management Co., Ltd.
Patent: EP2241315 A1, 2010 ;
反应条件
1.1: AlCl3, aluminium chloride / dichloromethane / 1.17 h / -75 - 0 °C / Inert atmosphere
1.2: Cooling with ice
2.1: potassium carbonate; methanol / 18 h / 20 °C
2.2: pH 5 - 6
View Scheme
参考文献
Zhang, Han-Cheng; Maryanoff, Bruce; White, Kimberly; Yabut, Stephen C.; Ye, Hong; Chen, Cailin
Patent: US2011/105490 A1, 2011 ;
US 20110105490 A1
反应条件
in benzene
Irradiation;
参考文献
Matsuura,T.; Kitaura,Y.
Tetrahedron, 1969 , vol. 25, p. 4501 - 4514
