2-羟基-4,6-二甲基苯甲醛合成路线 （共 15 条）
反应条件
sodium hydroxide; dipotassium peroxodisulfate anschliessend mit wss. HCl;
参考文献
Gruenanger; Cardani
Gazzetta Chimica Italiana, 1953 , vol. 83, p. 664,671
反应条件
triethylamine; magnesium chloride in acetonitrile
4 h; Heating / reflux;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1637527 A1, 2006 ;
Location in patent: Page/Page column 76 ;
EP 1637527 A1
反应条件
hydrogenchloride in sodium methylate; sodium
参考文献
NL Industries, Inc.
Patent: US4226792 A1, 1980 ;
反应条件
1: 3,5-dimethyl-phenol With triethylamine; magnesium chloride in acetonitrile
0.25 h;
2: formaldehyd 3 h; Heating;
参考文献
Knight, Paul D.; Clarkson, Guy; Hammond, Max L.; Kimberley, Brian S.; Scott, Peter
Journal of Organometallic Chemistry, 2005 , vol. 690, # 23 p. 5125 - 5144
反应条件
hydrogenchloride; aluminium trichloride; benzene
und anschliessend mit wss.HCl;
参考文献
Wilds; Djerassi
Journal of the American Chemical Society, 1946 , vol. 68, p. 1862
反应条件
silver trifluoromethanesulfonate in dichloromethane
T=0°C; 0.5 h; Inert atmosphere;
参考文献
Ohsawa, Kosuke; Yoshida, Masahito; Doi, Takayuki
Journal of Organic Chemistry, 2013 , vol. 78, # 7 p. 3438 - 3444
反应条件
trichlorophosphate
T=80 - 90°C;
参考文献
Raju, B.; Rao, G. S. Krishna
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 175 - 176
反应条件
trichlorophosphate
T=80 - 90°C;
参考文献
Raju, B.; Rao, G. S. Krishna
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 175 - 176
反应条件
boric acid; glycerol
T=150 - 160°C; und anschliessendes Erwaermen mit wss. H2SO4;
参考文献
Duff
Journal of the Chemical Society, 1941 , p. 547,549
反应条件
hydrogenchloride; aluminium trichloride; benzene
参考文献
v. Auwers; Saurwein
Chemische Berichte, 1922 , vol. 55, p. 2384
Full Text Show Details
Lindemann
Justus Liebigs Annalen der Chemie, 1923 , vol. 431, p. 276
