1-氨基环己烷-1-羧酸乙酯合成路线 （共 8 条）
参考文献
The Boots Company PLC
Patent: US5610161 A1, 1997 ;
反应条件
triethylamine in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethanol
参考文献
Shell Internationale Research Maatschappij B.V.
Patent: US4944791 A1, 1990 ;
反应条件
hydrogenchloride in ethanol 24 h; Ambient temperature;
参考文献
Kalvin, Douglas; Ramalingam, Kondareddiar; Woodward, Ronald
Synthetic Communications, 1985 , vol. 15, # 4 p. 267 - 272
反应条件
1: 1) LiHMDS / 1) THF, -78 deg C, 45 min, 2) THF, rt, 2 h 2: aq. HCl / diethyl ether / Ambient temperature View Scheme
参考文献
Kotha; Kuki
Tetrahedron Letters, 1992 , vol. 33, # 12 p. 1565 - 1568
反应条件
hydrogenchloride Destillieren des Hydrochlorids nach Zusatz von Bleihydroxyd unter vermindertem Druck;
参考文献
Zelinsky; Annenkow; Kulikow
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1911 , vol. 43, p. 1095
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1911 , vol. 73, p. 463
反应条件
ethanol; nickel T=100°C; P=257428 Torr; Hydrogenation;
参考文献
Jalce, Gael; Franck, Xavier; Figadere, Bruno
European Journal of Organic Chemistry, 2009 , # 3 p. 378 - 386
反应条件
1: diethyl ether 2: NaNO2, HCO2H View Scheme
参考文献
Johnston; McCaleb; Opliger; Montgomery
Journal of medicinal chemistry, 1966 , vol. 9, # 6 p. 892 - 911
反应条件
2: ethanolic KOH
View Scheme
参考文献
Godchot; Cauquil
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1935 , vol. 200, p. 1479
