1-(二甲基氨基)环己烷甲腈合成路线 (共 10 条)
反应条件
in water Ambient temperature;
参考文献
Yang; Bremont; Shen; Kefi; Langlois
European Journal of Medicinal Chemistry, 1996 , vol. 31, # 3 p. 231 - 239
反应条件
1: 1.) sodium bisulfite / 1.) water, RT, 30 min, 2.) RT, 2 h 2: H2O / 2 h / Ambient temperature View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 393, # 1 p. 143 - 152
反应条件
in water 2 h; Ambient temperature;
参考文献
Journal of Organometallic Chemistry, , vol. 393, # 1 p. 143 - 152
参考文献
Journal of Organic Chemistry, , vol. 23, p. 1112,1113
参考文献
Tetrahedron, , vol. 24, p. 4677 - 4688
反应条件
1.) 100 deg C, 1 min, room temperature, 2.) 100 deg C, 1 min, room temperature; Yield given. Multistep reaction;
参考文献
Synthetic Communications, , vol. 15, # 2 p. 157 - 164
反应条件
lithium aluminium tetrahydride; sulfuric acid in tetrahydrofuran T=40 - 50°C; 1 h;
参考文献
Yang; Bremont; Shen; Kefi; Langlois
European Journal of Medicinal Chemistry, 1996 , vol. 31, # 3 p. 231 - 239
反应条件
in tetrahydrofuran; diethyl ether 18 h; Ambient temperature;
参考文献
Lednicer, Daniel; VonVoigtlander, Philip F.; Emmert, D. Edward
Journal of Medicinal Chemistry, 1980 , vol. 23, # 4 p. 424 - 430
反应条件
(i) CF3SO3CH2CO2Et, (ii) DBU; Multistep reaction;
参考文献
Blinn, D.A.; Button, R.S.; Farazi, V.; Neeb, M.K.; Tapley, C.L.; et al.
Journal of Organometallic Chemistry, 1990 , vol. 393, # 1 p. 143 - 152
反应条件
hydrogenchloride; hydroxylamine
参考文献
Hollander et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 1112,1113